Literature DB >> 7492243

The semeiology of arthritis: discriminating between patients on the basis of their symptoms.

P S Helliwell1.   

Abstract

OBJECTIVES: To examine the intended meaning of words used by patients to describe arthritic symptoms, and to distinguish between different patient groups on the basis of these words.
METHODS: A Joint Symptom Questionnaire, developed to resemble the McGill Pain Questionnaire, was given to health professionals (n = 50) and patients with rheumatoid arthritis (RA) (n = 100), fibromyalgia (FM) (n = 50), ankylosing spondylitis (AS) (n = 50), and osteoarthritis (OA) (n = 50). Respondents were invited to define each word by selecting an appropriate heading. Comparison of patient groups was based on the selection of words they chose to describe their joint symptoms.
RESULTS: Between health professionals and patients there were no semantic differences in the words given. Patients with FM chose more words to describe their symptoms than the other patient groups (RA median nine words; AS nine words; OA 10 words; FM 12 words). Using receiver operating characteristic curves, a clear distinction between patients with RA, FM, and AS was found, but patients with RA were not readily separated from patients with OA.
CONCLUSIONS: There appears to be no semeiological confusion between health professionals and patients regarding arthritic symptoms. However, the spectrum of words chosen by patients to describe the feelings in their joints permits a separation between patients with RA, AS, and FM. Using this questionnaire, patients with RA and OA are symptomatically similar.

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Year:  1995        PMID: 7492243      PMCID: PMC1010044          DOI: 10.1136/ard.54.11.924

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  10 in total

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Authors:  J M Hazes; R Hayton; A J Silman
Journal:  J Rheumatol       Date:  1993-07       Impact factor: 4.666

  10 in total
  2 in total

1.  CD38 and E2F transcription factor 2 have uniquely increased expression in rheumatoid arthritis synovial tissues.

Authors:  X Chang; L Yue; W Liu; Y Wang; L Wang; B Xu; Y Wang; J Pan; X Yan
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2.  Increased expression of carbonic anhydrase I in the synovium of patients with ankylosing spondylitis.

Authors:  Xiaotian Chang; Jinxiang Han; Yan Zhao; Xinfeng Yan; Shui Sun; Yazhou Cui
Journal:  BMC Musculoskelet Disord       Date:  2010-12-08       Impact factor: 2.362

  2 in total

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