Literature DB >> 7492118

Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.

F Reyna1, M Huesca, V González, L Y Fuchs.   

Abstract

Spontaneous quinolone-resistant mutants obtained from Salmonella typhimurium Su694 were screened for mutations by direct DNA sequencing of an amplified PCR gyrA fragment. Substitutions Ser-83-->Phe (Ser83Phe), Ser83Tyr, Asp87Tyr, and Asp87Asn and double mutation Ala67Pro-Gly81Ser, which resulted in decreased sensitivities to ciprofloxacin, enoxacin, pefloxacin, norfloxacin, ofloxacin, and nalidixic acid, were found. The levels of resistance to quinolones for each mutant were determined.

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Year:  1995        PMID： 7492118      PMCID： PMC162795          DOI： 10.1128/AAC.39.7.1621

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  37 in total

1.  Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.

Authors:  H E Takiff; L Salazar; C Guerrero; W Philipp; W M Huang; B Kreiswirth; S T Cole; W R Jacobs; A Telenti
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

2.  Characterization of fluoroquinolone-resistant mutants of escherichia coli selected in vitro.

Authors:  P Heisig; R Tschorny
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

3.  Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs.

Authors:  J Vila; J Ruiz; F Marco; A Barcelo; P Goñi; E Giralt; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

4.  Detection of 4-quinolone resistance mutation in gyrA gene of Shigella dysenteriae type 1 by PCR.

Authors:  M Rahman; G Mauff; J Levy; M Couturier; G Pulverer; N Glasdorff; J P Butzler
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

5.  Characterization of mutations in Mycobacterium smegmatis involved in resistance to fluoroquinolones.

Authors:  V Revel; E Cambau; V Jarlier; W Sougakoff
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

6.  Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates.

Authors:  A Kureishi; J M Diver; B Beckthold; T Schollaardt; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

7.  Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus.

Authors:  H Ito; H Yoshida; M Bogaki-Shonai; T Niga; H Hattori; S Nakamura
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

8.  Analysis by PCR and direct DNA sequencing of gyrA mutations associated with fluoroquinolone resistance in Enterococcus faecalis.

Authors:  V Korten; W M Huang; B E Murray
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

9.  High-level fluoroquinolone resistance in a Salmonella typhimurium isolate due to alterations in both gyrA and gyrB genes.

Authors:  P Heisig
Journal:  J Antimicrob Chemother       Date:  1993-09       Impact factor: 5.790

10.  Amplification and nucleotide sequence of the quinolone resistance-determining region in the gyrA gene of mycobacteria.

Authors:  E Cambau; W Sougakoff; V Jarlier
Journal:  FEMS Microbiol Lett       Date:  1994-02-01       Impact factor: 2.742
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  27 in total

1.  gyrA Mutations associated with nalidixic acid-resistant salmonellae from wild birds.

Authors:  M Paloma Reche; José E García de los Ríos; Pedro A Jiménez; Ana M Rojas; Rafael Rotger
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

2.  New quinolone resistance phenomenon in Salmonella enterica: nalidixic acid-susceptible isolates with reduced fluoroquinolone susceptibility.

Authors:  Antti J Hakanen; Marianne Lindgren; Pentti Huovinen; Jari Jalava; Anja Siitonen; Pirkko Kotilainen
Journal:  J Clin Microbiol       Date:  2005-11       Impact factor: 5.948

Review 3.  DNA gyrase, topoisomerase IV, and the 4-quinolones.

Authors:  K Drlica; X Zhao
Journal:  Microbiol Mol Biol Rev       Date:  1997-09       Impact factor: 11.056

4.  Cloning and nucleotide sequence of the DNA gyrase gyrA gene from the fish pathogen Aeromonas salmonicida.

Authors:  H Oppegaard; H Sørum
Journal:  Antimicrob Agents Chemother       Date:  1996-05       Impact factor: 5.191

5.  Using In Vitro Dynamic Models To Evaluate Fluoroquinolone Activity against Emergence of Resistant Salmonella enterica Serovar Typhimurium.

Authors:  Seung-Jin Lee; Elias Gebru Awji; Na-Hye Park; Seung-Chun Park
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

6.  Amino acid substitutions in GyrA of Burkholderia glumae are implicated in not only oxolinic acid resistance but also fitness on rice plants.

Authors:  Yukiko Maeda; Akinori Kiba; Kouhei Ohnishi; Yasufumi Hikichi
Journal:  Appl Environ Microbiol       Date:  2006-12-28       Impact factor: 4.792

7.  DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A.

Authors:  Kenji Hirose; Ai Hashimoto; Kazumichi Tamura; Yoshiaki Kawamura; Takayuki Ezaki; Hiroko Sagara; Haruo Watanabe
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

8.  gyrA polymorphism in Campylobacter jejuni: detection of gyrA mutations in 162 C. jejuni isolates by single-strand conformation polymorphism and DNA sequencing.

Authors:  Antti Hakanen; Jari Jalava; Pirkko Kotilainen; Hannele Jousimies-Somer; Anja Siitonen; Pentti Huovinen
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

9.  Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli.

Authors:  P Heisig
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

10.  Mutations in gyrA gene of quinolone-resistant Salmonella serotypes isolated from humans and animals.

Authors:  D J Griggs; K Gensberg; L J Piddock
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191
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