| Literature DB >> 12234852 |
Kenji Hirose1, Ai Hashimoto, Kazumichi Tamura, Yoshiaki Kawamura, Takayuki Ezaki, Hiroko Sagara, Haruo Watanabe.
Abstract
The mutations that are responsible for fluoroquinolone resistance in the gyrA, gyrB, parC, and parE genes of Salmonella enterica serovar Typhi and serovar Paratyphi A were investigated. The sequences of the quinolone resistance-determining region of the gyrA gene in clinical isolates which showed decreased susceptibilities to fluoroquinolones had a single mutation at either the Ser-83 or the Asp-87 codon, and no mutations were found in the gyrB, parC, and parE genes.Entities:
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Year: 2002 PMID: 12234852 PMCID: PMC128770 DOI: 10.1128/AAC.46.10.3249-3252.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191