E D Whitman1, A M Boatman. 1. Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Abstract
BACKGROUND: Implanted venous access port infection can be difficult to diagnose and treat. If device removal is necessary, confirming port infection is problematic. MATERIALS AND METHODS: Culture specimens from three sites, catheter tip (Tip), port pocket, and the material within the reservoir (Inside), were sent from ports removed for potential infection. The results of these cultures were compared to preremoval peripheral and central blood cultures. RESULTS: Forty-five ports were removed for suspected infection. Confirmed port infection was defined as positive culture(s) from one or more experimental specimen(s). In 29 evaluable cases, the Inside specimens were completely predictive. Tip specimens were less accurate, even with a lower diagnostic threshold. In 7 of 19 confirmed infections, only the Inside culture was diagnostic. CONCLUSION: The most predictive culture specimen in a potentially infected port is the thrombotic material inside the reservoir.
BACKGROUND: Implanted venous access port infection can be difficult to diagnose and treat. If device removal is necessary, confirming port infection is problematic. MATERIALS AND METHODS: Culture specimens from three sites, catheter tip (Tip), port pocket, and the material within the reservoir (Inside), were sent from ports removed for potential infection. The results of these cultures were compared to preremoval peripheral and central blood cultures. RESULTS: Forty-five ports were removed for suspected infection. Confirmed port infection was defined as positive culture(s) from one or more experimental specimen(s). In 29 evaluable cases, the Inside specimens were completely predictive. Tip specimens were less accurate, even with a lower diagnostic threshold. In 7 of 19 confirmed infections, only the Inside culture was diagnostic. CONCLUSION: The most predictive culture specimen in a potentially infected port is the thrombotic material inside the reservoir.
Authors: Leonard A Mermel; Michael Allon; Emilio Bouza; Donald E Craven; Patricia Flynn; Naomi P O'Grady; Issam I Raad; Bart J A Rijnders; Robert J Sherertz; David K Warren Journal: Clin Infect Dis Date: 2009-07-01 Impact factor: 9.079
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