Literature DB >> 7490219

Phosphonothrixin, a novel herbicidal antibiotic produced by Saccharothrix sp. ST-888. II. Structure determination.

T Kimura1, K Nakamura, E Takahashi.   

Abstract

Phosphonothrixin (1) is a novel herbicidal agent produced by Saccharothrix sp. ST-888. This unique compound possessing a C-P bond and an isoprene unit was determined to be 2-hydroxy-2-hydroxymethyl-3-oxobutyl-phosphonic acid. Unusually rapid proton-deuterium (H-D) exchange of the methyl ketone unit of this antibiotic in D2O solution was observed. Phosphonothrixin can be classified as a new type of natural product herbicide having a C-P bond in the molecule.

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Year:  1995        PMID: 7490219     DOI: 10.7164/antibiotics.48.1130

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  4 in total

1.  Identification of the biosynthetic gene cluster for the herbicide phosphonothrixin in Saccharothrix sp. ST-888.

Authors:  Jianwen Lin; Makoto Nishiyama; Tomohisa Kuzuyama
Journal:  J Antibiot (Tokyo)       Date:  2014-10-29       Impact factor: 2.649

2.  Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis.

Authors:  B M Lange; R E Ketchum; R B Croteau
Journal:  Plant Physiol       Date:  2001-09       Impact factor: 8.340

Review 3.  Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways.

Authors:  Kou-San Ju; James R Doroghazi; William W Metcalf
Journal:  J Ind Microbiol Biotechnol       Date:  2013-11-24       Impact factor: 3.346

4.  Bioprospecting of Soil-Derived Actinobacteria Along the Alar-Hotan Desert Highway in the Taklamakan Desert.

Authors:  Shaowei Liu; Ting Wang; Qinpei Lu; Feina Li; Gang Wu; Zhongke Jiang; Xugela Habden; Lin Liu; Xiaolin Zhang; Dmitry A Lukianov; Ilya A Osterman; Petr V Sergiev; Olga A Dontsova; Chenghang Sun
Journal:  Front Microbiol       Date:  2021-03-15       Impact factor: 5.640

  4 in total

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