Literature DB >> 7480210

A cytotoxic diacetylene from Dendropanax arboreus.

W N Setzer, T J Green, K W Whitaker, D M Moriarity, C A Yancey, R O Lawton, R B Bates.   

Abstract

The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and identified by 1H- and 13C-NMR spectroscopy as the acetylenic compound cis-1,9,16-heptadecatriene-4,6-diyne-3,8-diol.

Entities:  

Mesh:

Substances:

Year:  1995        PMID: 7480210     DOI: 10.1055/s-2006-958139

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  3 in total

Review 1.  Anticancer activity of natural and synthetic acetylenic lipids.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-10       Impact factor: 1.880

2.  Medicinal and ethnoveterinary remedies of hunters in Trinidad.

Authors:  C Lans; T Harper; K Georges; E Bridgewater
Journal:  BMC Complement Altern Med       Date:  2001-11-30       Impact factor: 3.659

3.  New Chemical Constituents from the Bark of Dendropanax morbifera Leveille and their Evaluation of Antioxidant Activities.

Authors:  Ill-Min Chung; Seung-Hyun Kim; Chang Kwon; So-Yeon Kim; Yu-Jin Yang; Ju-Sung Kim; Mohd Ali; Ateeque Ahmad
Journal:  Molecules       Date:  2019-11-01       Impact factor: 4.411

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.