Literature DB >> 7463156

Myocardial imaging in man with I-123 meta-iodobenzylguanidine.

R C Kline, D P Swanson, D M Wieland, J H Thrall, M D Gross, B Pitt, W H Beierwaltes.   

Abstract

Meta-[123I]iodobenzylguanidine (m-[123I]IBG), a guanethidine analog, was used to image the myocardium in five normal male volunteers. Each subject received 2.0 mCi m-[123I]IBG intravenously. Four were given a bolus injection. Multiple myocardial scintigrams were obtained over a 2-hr period. Myocardial uptake was calculated by dividing the decay-corrected global myocardial count rate (after interpolated background correction) by the peak count rate during the first passage of the m-[123I]IBG bolus through the heart. The left ventricle could be visualized within 1-2 min of m-[123I]IBG injection. Mean myocardial uptake was 0.63% (range 0.45-0.78%) of injected dose at 5 min, and 0.76% (range 0.49-0.93%) at 2 hr (n = 4). m-[123I]IBG may provide quantitative information on myocardial catecholamine content.

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Year:  1981        PMID： 7463156

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  68 in total

Review 1.  MIBG imaging.

Authors:  Amar D Patel; Ami E Iskandrian
Journal:  J Nucl Cardiol       Date:  2002 Jan-Feb       Impact factor: 5.952

Review 2.  Cardiac receptor physiology and its application to clinical imaging: present and future.

Authors:  H Tseng; J M Link; J R Stratton; J H Caldwell
Journal:  J Nucl Cardiol       Date:  2001 May-Jun       Impact factor: 5.952

Review 3.  Radionuclide imaging of cardiac autonomic innervation.

Authors:  Sang Yong Ji; Mark I Travin
Journal:  J Nucl Cardiol       Date:  2010-08       Impact factor: 5.952

4.  Immunohistochemical-scintigraphic correlation of sympathetic cardiac innervation in postischemic left ventricular aneurysms.

Authors:  Mario Gaudino; Alessandro Giordano; Pietro Santarelli; Francesco Alessandrini; Stefania Lucia Nori; Carlo Trani; Simona Gaudino; Gianfederico Possati
Journal:  J Nucl Cardiol       Date:  2002 Nov-Dec       Impact factor: 5.952

5.  Myocardial (123) I-metaiodobenzylguanidine washout and heart rate variability in asymptomatic subjects.

Authors:  Sakari Simula; Esko Vanninen; Antti Hedman; Seppo Lehto; Jyrki Kuikka; Juha Hartikainen
Journal:  Ann Noninvasive Electrocardiol       Date:  2012-01       Impact factor: 1.468

6.  Prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy: comparison of 123I-MIBG scintigraphy and low-dose dobutamine stress echocardiography.

Authors:  Konghow Lee; Masao Daimon; Youichi Kuwabara; Rei Hasegawa; Tomohiko Toyoda; Tai Sekine; Takayuki Kawata; Issei Komuro
Journal:  J Echocardiogr       Date:  2009-09-11

7.  Long-term course and cardiac sympathetic nerve activity in patients with hypertrophic cardiomyopathy.

Authors:  M Shimizu; N Sugihara; Y Kita; K Shimizu; Y Horita; K Nakajima; J Taki; R Takeda
Journal:  Br Heart J       Date:  1992-02

8.  Serial assessment of denervated but viable myocardium following acute myocardial infarction in dogs using iodine-123 metaiodobenzylguanidine and thallium-201 chloride myocardial single photon emission tomography.

Authors:  T Nishimura; H Oka; M Sago; T Matsuo; T Uehara; H Noda; H Takano
Journal:  Eur J Nucl Med       Date:  1992

Review 9.  Tako-tsubo cardiomyopathy: how to understand possible pathophysiological mechanism and the role of (123)I-MIBG imaging.

Authors:  Derk O Verschure; G Aernout Somsen; Berthe L F van Eck-Smit; Remco J J Knol; Jan Booij; Hein J Verberne
Journal:  J Nucl Cardiol       Date:  2014-01-25       Impact factor: 5.952

10.  I-123 MIBG cardiac scintigraphy and autonomic test evaluation in multiple sclerosis patients.

Authors:  Mordechai Lorberboym; Yair Lampl; Galina Nikolov; Menachem Sadeh; Ronit Gilad
Journal:  J Neurol       Date:  2008-02-20       Impact factor: 4.849
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