Literature DB >> 7462299

Possible in vivo formation of a carcinogenic substance from diethyl pyrocarbonate and ammonia.

E Uzvölgyi, F Boján.   

Abstract

Development of lung tumors can be observed in Kid: CFLP mice treated intragastrically with diethyl pyrocarbonate and ammonia. The lung tumors may result from a carcinogenic substance, supposedly urethane, formed in vivo from diethyl pyrocarbonate in the presence of ammonia.

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Year:  1980        PMID： 7462299     DOI： 10.1007/bf00409907

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  4 in total

Review 1.  Lung tumors in mice: application to carcinogenesis bioassay.

Authors:  M B Shimkin; G D Stoner
Journal:  Adv Cancer Res       Date:  1975       Impact factor: 6.242

2.  Ethylcarbamate in fermented beverages and foods. II. Possible formation of ethylcarbamate from diethyl dicarbonate addition to wine.

Authors:  C S Ough
Journal:  J Agric Food Chem       Date:  1976 Mar-Apr       Impact factor: 5.279

3.  Diethyl pyrocarbonate: formation of urethan in treated beverages.

Authors:  G Löfroth; T Gejvall
Journal:  Science       Date:  1971-12-17       Impact factor: 47.728

4.  A dose-response study on urethane carcinogenesis in rats and mice.

Authors:  D Schmähl; R Port; J Wahrendorf
Journal:  Int J Cancer       Date:  1977-01       Impact factor: 7.396
  4 in total

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