| Literature DB >> 7456934 |
J Krupińska, H Sobański, J Piotrowicz, B Cebo, J Mazur.
Abstract
Simulataneous oral administration of butylhydroxytoluene (BHT) (50 or 100 mg/kg) with indomethacin (IND) (3, 6 or 20 mg/kg) prevented the damaging effect of IND on the rat gastric mucosa. Butylhydroxyanisole (BHA) and nordihydroguiaretic acid (NDGA) rather potentiated than prevented the noxious action of IND. A reduction of IND toxicity without affecting its anti-inflammatory action seems to be possible to achieve by concomitant administration of IND with BHT.Entities:
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Year: 1980 PMID： 7456934
Source DB: PubMed Journal: Acta Biol Med Ger ISSN： 0001-5318