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Literature DB >> 745656

Inhibition of gamma-aminobutyric acid release from rat cerebral cortex slices by barbiturate anesthesia.

Abstract

Amobarbital and pentobarbital anesthesia inhibited the potassium-stimulated, Ca-dependent release of gamma-aminobutyric acid (GABA) from rat cerebral cortex slices during incubation in vitro. Inhibition of GABA release was not found when slices were prepared from rats shortly after they awakened from amobarbital anesthesia. Phenobarbital anesthesia did not affect the release of GABA.

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Year: 1978 PMID： 745656 DOI： 10.1007/bf00966324

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

14 in total

1. Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates.

Authors: R A Nicoll; J C Eccles; T Oshima; F Rubia
Journal: Nature Date: 1975-12-18 Impact factor: 49.962

2. Barbiturate inhibition of calcium uptake by depolarized nerve terminals in vitro.

Authors: M P Blaustein; A C Ector
Journal: Mol Pharmacol Date: 1975-05 Impact factor: 4.436

3. Pentobarbital selectively enhances GABA-mediated post-synaptic inhibition in tissue cultured mouse spinal neurons.

Authors: B R Ransom; J L Barker
Journal: Brain Res Date: 1976-09-24 Impact factor: 3.252

4. Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release.

Authors: J W Haycock; W B Levy; C W Cotman
Journal: Biochem Pharmacol Date: 1977-01-15 Impact factor: 5.858

5. The selective depression of evoked cortical EPSPs by pentobarbitone.

Authors: C D Richards
Journal: J Physiol Date: 1971 Impact factor: 5.182

6. Effect of barbiturates on 'quantal' synaptic transmission in spinal motoneurones.

Authors: J N Weakly
Journal: J Physiol Date: 1969-09 Impact factor: 5.182

7. Sodium ion movements and the spontaneous and electrically stimulated release of ( 3 H)GABA and ( 14 C)glutamic acid from rat cortical slices.

Authors: J P Hammerstad; R W Cutler
Journal: Brain Res Date: 1972-12-12 Impact factor: 3.252

8. Release of gamma-aminobutyric acid from hippocampal slices of the rat following generalized seizures induced by daily electrical stimulation of entorhinal cortex.

Authors: N R Liebowitz; T A Pedley; R W Cutler
Journal: Brain Res Date: 1977-12-16 Impact factor: 3.252

Inhibition of gamma-aminobutyric acid release from rat cerebral cortex slices by barbiturate anesthesia.

1. Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates.

2. Barbiturate inhibition of calcium uptake by depolarized nerve terminals in vitro.

3. Pentobarbital selectively enhances GABA-mediated post-synaptic inhibition in tissue cultured mouse spinal neurons.

4. Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release.

5. The selective depression of evoked cortical EPSPs by pentobarbitone.

6. Effect of barbiturates on 'quantal' synaptic transmission in spinal motoneurones.

7. Sodium ion movements and the spontaneous and electrically stimulated release of ( 3 H)GABA and ( 14 C)glutamic acid from rat cortical slices.

8. Release of gamma-aminobutyric acid from hippocampal slices of the rat following generalized seizures induced by daily electrical stimulation of entorhinal cortex.

9. The effect of barbiturates on (3H)GABA transport in rat cerebral cortex slices.

10. Regional changes in amino acid content in developing rat brain.

1. Effect of barbiturates on release endogenous amino acids from rat cortex slices.

2. Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones.