| Literature DB >> 7452288 |
T S Brannan, H S Maker, C Weiss, G Cohen.
Abstract
Glutathione peroxidase activity was measured in 10 areas of perfused adult rat brain with the use of a fluorometric assay coupled to NADPH oxidation. The caudate-putamen and the substantia nigra had the highest activities. Cortical areas and several nuclear areas had somewhat lower activity. Activity was lowest in a white matter structure (corpus callosum). High activity of glutathione peroxidase may be related to the need to reduce hydrogen peroxide arising in the course of monoamine metabolism.Entities:
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Year: 1980 PMID： 7452288 DOI： 10.1111/j.1471-4159.1980.tb07102.x
Source DB: PubMed Journal: J Neurochem ISSN： 0022-3042 Impact factor: 5.372