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Literature DB >> 7449920

Effect of chronic administration of morphine on primary immune response in mice.

M Güngör, E Genç, H Sağduyu, L Eroğlu, H Koyuncuoğlu.

Abstract

The effect of 3 different doses of chronically-administered morphine on the primary immune response was studied in mice by estimating spleen/body weight ratio and serum hemolysin production against sheep red blood cells (SRBC). It was observed that morphine exerted a dose-dependent inhibitory effect on the immune response which was antagonized by the concomitant administration of naloxone. The findings suggest that the inhibitory effect of morphine is specific.

Entities: Chemical Species

Mesh：

Substances：

Year: 1980 PMID： 7449920 DOI： 10.1007/bf01969606

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

16 in total

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Journal: Ann Surg Date: 1964-05 Impact factor: 12.969

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Authors: R K Datta; W Antopol
Journal: Brain Res Date: 1973-04-27 Impact factor: 3.252

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Authors: N Wurster; P Elsbach; J Rand; E J Simon
Journal: Biochim Biophys Acta Date: 1971-11-05

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Authors: D H Clouet; M Ratner
Journal: Brain Res Date: 1967-02 Impact factor: 3.252

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Authors: W F Geber; S S Lefkowitz; C Y Hung
Journal: Arch Int Pharmacodyn Ther Date: 1975-04

9 in total

Review 1. Detection and function of opioid receptors on cells from the immune system.

Authors: J M Bidlack
Journal: Clin Diagn Lab Immunol Date: 2000-09

2. Aggravation by morphine and D-aspartic acid of pyelonephritis induced by i.v. inoculation of Staphylococcus aureus in rats.

Authors: H Koyuncuoğlu; M Güngör; O Anğ; D Inanç; M Anğ-Küçüker; H Sağduyu; V Uysal
Journal: Infection Date: 1988 Impact factor: 3.553

Review 3. Opioid receptors and signaling on cells from the immune system.

Authors: Jean M Bidlack; Maxim Khimich; Amy L Parkhill; Sarah Sumagin; Baoyong Sun; Christopher M Tipton
Journal: J Neuroimmune Pharmacol Date: 2006-07-08 Impact factor: 4.147

Review 4. Injecting drugs of abuse and immunity: implications for HIV vaccine testing and efficacy.

Authors: Kenneth E Ugen; Susan B Nyland
Journal: Springer Semin Immunopathol Date: 2006-10-13

5. The inhibition by morphine and D-aspartic acid of antibody production against Salmonella typhimurium antigen in rats: its antagonism by L-aspartic acid.

Authors: H Koyuncouğlu; O Anğ; D Inanç; H Sağduyu; M Güngör
Journal: Agents Actions Date: 1987-02