Literature DB >> 744691

Preparation and properties of tritiated human beta-endorphin with high specific radioactivity.

R A Houghten, C H Li.   

Abstract

Tritiated human beta-endorphin, specifically labelled at Tyr27, has been prepared with 50 Ci/mmol. Various physicochemical investigations indicated that tritiated peptide is identical with the native betah-endorphin. In addition, opiate activity of the tritiated product possesses the same potency as the native peptide.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 744691     DOI： 10.1111/j.1399-3011.1978.tb02904.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN： 0367-8377


  12 in total

1.  Properties and localization of beta-endorphin receptor in rat brain.

Authors:  P Y Law; H H Loh; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

2.  Characterization of solubilized human and rat brain beta-endorphin-receptor complex.

Authors:  D M Helmeste; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

3.  Preparation of [125I-Tyr27,Leu5]beta h-endorphin and its use for crosslinking of opioid binding sites in human striatum and NG108-15 neuroblastoma-glioma cells.

Authors:  D M Helmeste; R G Hammonds; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

4.  beta-Endorphin-induced analgesia is inhibited by synthetic analogs of beta-endorphin.

Authors:  P Nicolas; R G Hammonds; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

5.  Characterization of beta-endorphin binding protein (receptor) from rat brain membranes.

Authors:  R G Hammonds; P Nicolas; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

6.  beta-Endorphin: characteristics of binding sites in rabbit spinal cord.

Authors:  P Ferrara; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

7.  beta-Endorphin omission analogs: dissociation of immunoreactivity from other biological activities.

Authors:  C H Li; D Yamashiro; L F Tseng; W C Chang; P Ferrara
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

8.  Beta-endorphin: opiate receptor binding activities of six naturally occurring beta-endorphin homologs studied by using tritiated human hormone and naloxone as primary ligands--effects of sodium ion.

Authors:  P Nicolas; R G Hammonds; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

9.  Beta-Endorphin: dissociation of receptor binding activity from analgesic potency.

Authors:  C H Li; L F Tseng; P Ferrara; D Yamashiro
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

10.  beta-Endorphin: stability, clearance behavior, and entry into the central nervous system after intravenous injection of the tritiated peptide in rats and rabbits.

Authors:  R A Houghten; R W Swann; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.