Literature DB >> 7442812

Silent nucleotide substitutions during evolution.

T H Jukes.   

Abstract

Silent nucleotide substitutions in evolution are found by comparing homologous sequences of DNA from different organisms. Silent changes are common in the third bases of codons, so that no changes takes place in the specified amino acid. Silent changes average about half of the total nucleotide substitutions during evolution of protein-coding regions of genes. Nucleotide substitutions also take place during evolution in non-coding regions of DNA, such as in intervening sequences and in sequences that precede and follow codon regions in genes. Deletions and additions from events of recombination, in addition to nucleotide substitutions, are common in these non-coding regions.

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Year:  1980        PMID： 7442812     DOI： 10.1007/bf00450662

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN： 0028-1042


  16 in total

1.  The nucleotide sequence and genome organization of the polyoma early region: extensive nucleotide and amino acid homology with SV40.

Authors:  T Friedmann; A Esty; P LaPorte; P Deininger
Journal:  Cell       Date:  1979-07       Impact factor: 41.582

2.  Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns.

Authors:  J van den Berg; A van Ooyen; N Mantei; A Schamböck; G Grosveld; R A Flavell; C Weissmann
Journal:  Nature       Date:  1978-11-02       Impact factor: 49.962

3.  Molecular evolution of human and rabbit beta-globin mRNAs.

Authors:  F C Kafatos; A Efstratiadis; B G Forget; S M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

4.  The histone H4 gene of Strongylocentrotus purpuratus: DNA and mRNA sequences at the 5' end.

Authors:  M Grunstein; J E Grunstein
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1978

5.  Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison.

Authors:  B P Nichols; C Yanofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

6.  Improved procedures for comparing homologous sequences in molecules of proteins and nucleic acids.

Authors:  R Holmquist; C Cantor; T Jukes
Journal:  J Mol Biol       Date:  1972-02-28       Impact factor: 5.469

7.  Sequence of the human insulin gene.

Authors:  G I Bell; R L Pictet; W J Rutter; B Cordell; E Tischer; H M Goodman
Journal:  Nature       Date:  1980-03-06       Impact factor: 49.962

8.  The structure and evolution of the two nonallelic rat preproinsulin genes.

Authors:  P Lomedico; N Rosenthal; A Efstratidadis; W Gilbert; R Kolodner; R Tizard
Journal:  Cell       Date:  1979-10       Impact factor: 41.582

9.  Codon--anticodon pairing: the wobble hypothesis.

Authors:  F H Crick
Journal:  J Mol Biol       Date:  1966-08       Impact factor: 5.469

10.  BK virus DNA: complete nucleotide sequence of a human tumor virus.

Authors:  R C Yang; R Wu
Journal:  Science       Date:  1979-10-26       Impact factor: 47.728
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  1 in total

1.  Estimation of evolutionary distances between homologous nucleotide sequences.

Authors:  M Kimura
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205
  1 in total

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