Literature DB >> 7439260

Elevated serum parathyroid hormone concentration during treatment with high ceiling diuretics.

J Elmgreen, L Tougaard, A Leth, M S Christensen.   

Abstract

Serum concentrations of parathyroid hormone (s-PTH) calcium, phosphorus and alkaline phosphatase were measured during treatment with furosemide or bumetanide for congestive heart failure. Significant elevations both of s-PTH and alkaline phosphatase were found, whereas serum calcium concentration was decreased. The changes were not related to the dose of drug or to the duration of treatment. It is concluded that treatment with furosemide or bumetanide may cause hypocalcaemia, resulting in elevation of s-PTH. The increased concentration of alkaline phosphatase may indicate accelerated bone remodelling, as found in primary hyperparathyroidism.

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Year:  1980        PMID： 7439260     DOI： 10.1007/bf00561397

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  7 in total

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5.  Acute treatment of hypercalcemia with furosemide.

Authors:  W N Suki; J J Yium; M Von Minden; C Saller-Hebert; G Eknoyan; M Martinez-Maldonado
Journal:  N Engl J Med       Date:  1970-10-15       Impact factor: 91.245

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Authors:  M S Christensen
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7.  Evidence for secondary hyperparathyroidism in idiopathic hypercalciuria.

Authors:  F L Coe; J M Canterbury; J J Firpo; E Reiss
Journal:  J Clin Invest       Date:  1973-01       Impact factor: 14.808
  7 in total
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7.  Elevated blood pressure, antihypertensive medications and bone health in the population: revisiting old hypotheses and exploring future research directions.

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Review 8.  The Effects of Osteoporotic and Non-osteoporotic Medications on Fracture Risk and Bone Mineral Density.

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  8 in total

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