| Literature DB >> 743903 |
C G Sahasrabuddhe, S Pathak, T C Hsu.
Abstract
Digestion of fixed metaphase chromosomes by endonucleases (micrococcal nuclease and DNase II) under optimal digestion conditions followed by Giemsa staining produces sharp banding patterns identical to G-bands. In 3H-thymidine labeled, synchronized metaphase cells of the chinese hamster (CHO line), the band induction is accompanied by the removal of DNA. The single strand specific nuclease S1 and DNase I do not produce such banding patterns.Entities:
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Year: 1978 PMID: 743903 DOI: 10.1007/bf00332136
Source DB: PubMed Journal: Chromosoma ISSN: 0009-5915 Impact factor: 4.316