Literature DB >> 7437776

Role of drugs in traffic accidents.

R Honkanen, L Ertama, M Linnoila, A Alha, I Lukkari, M Karlsson, O Kiviluoto, M Puro.   

Abstract

Serum samples from 201 drivers who presented at emergency departments within six hours after being injured in a road accident and 325 control drivers selected randomly at petrol stations were screened for drugs by combined thin-layer and gas chromatography. Blood alcohol concentrations were also measured, and a questionnaire on the subjects' state of health and use of drugs administered. At interview 30 patients (15%) and 44 controls (13%) said that they had taken drugs in the previous 24 hours. Four patients (2%) and six controls (2%) said that they had taken psychotropic drugs, but serum analysis detected psychotropic drugs in 10 patients (5%) and eight controls (2.5%). Diazepam was found in 16 of the 18 subjects in whom psychotropic drugs were detected. Alcohol was detected in 30 patients (15%) and three controls (1%). Drug use appeared to be somewhat lower in Finland than in other Western countries, and illness to be a more important traffic hazard than drugs in general. Interview was not a reliable method of establishing whether drivers had taken psychotropic drugs. Taking diazepam may increase the risk of being involved in a traffic accident, but alcohol was the most powerful risk factor.

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Year:  1980        PMID: 7437776      PMCID: PMC1714792          DOI: 10.1136/bmj.281.6251.1309

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  8 in total

1.  Prevalence of drugs among drivers arrested for drinking and driving in Finland.

Authors:  A R Alha; M Karlsson; M Linnoila; I Lukkari
Journal:  Z Rechtsmed       Date:  1977-04-18

2.  Rapid determination of salicylate in biological fluids.

Authors:  P TRINDER
Journal:  Biochem J       Date:  1954-06       Impact factor: 3.857

3.  The development of a blood paracetamol estimation kit.

Authors:  S E Kendal; G Lloyd-Jones; C F Smith
Journal:  J Int Med Res       Date:  1976       Impact factor: 1.671

4.  Plasma propranolol levels in adults with observations in four children.

Authors:  D G Shand; E M Nuckolls; J A Oates
Journal:  Clin Pharmacol Ther       Date:  1970 Jan-Feb       Impact factor: 6.875

5.  A review of the safety hazard due to poor health, drugs, and their interaction.

Authors:  F B Benjamin
Journal:  Hum Factors       Date:  1977-04       Impact factor: 2.888

6.  Effect of drugs and alcohol on psychomotor skills related to driving.

Authors:  M Linnoila
Journal:  Ann Clin Res       Date:  1974-02

7.  Minor tranquillisers and road accidents.

Authors:  D C Skegg; S M Richards; R Doll
Journal:  Br Med J       Date:  1979-04-07

8.  A case-control study on alcohol as a risk factor in pedestrian accident. A preliminary report.

Authors:  R Honkanen; L Ertama; P Kuosmanen; M Linnoila; T Visuri
Journal:  Mod Probl Pharmacopsychiatry       Date:  1976
  8 in total
  18 in total

Review 1.  The impact of medicinal drugs on traffic safety: a systematic review of epidemiological studies.

Authors:  Ludivine Orriols; Louis-Rachid Salmi; Pierre Philip; Nicholas Moore; Bernard Delorme; Anne Castot; Emmanuel Lagarde
Journal:  Pharmacoepidemiol Drug Saf       Date:  2009-08       Impact factor: 2.890

2.  Prescription of antidepressants and the risk of road traffic crash in the elderly: a case-crossover study.

Authors:  Ludivine Orriols; Machelle Wilchesky; Emmanuel Lagarde; Samy Suissa
Journal:  Br J Clin Pharmacol       Date:  2013-11       Impact factor: 4.335

Review 3.  Benzodiazepine use and motor vehicle accidents. Systematic review of reported association.

Authors:  R E Thomas
Journal:  Can Fam Physician       Date:  1998-04       Impact factor: 3.275

4.  [Role of drugs in traffic accidents. A pilot study of traffic accident offenders in Switzerland (Bern region)].

Authors:  L Ulrich; O Rudin; A Amsler; P Zink
Journal:  Z Rechtsmed       Date:  1984

Review 5.  Traffic accidents and minor tranquilizers: a review.

Authors:  R L Bauer
Journal:  Public Health Rep       Date:  1984 Nov-Dec       Impact factor: 2.792

6.  Sedating drugs and automobile accidents leading to hospitalization.

Authors:  H Jick; J R Hunter; B J Dinan; S Madsen; A Stergachis
Journal:  Am J Public Health       Date:  1981-12       Impact factor: 9.308

7.  Buspirone: an anxiolytic without sedative effect.

Authors:  W F Seidel; S A Cohen; N G Bliwise; W C Dement
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

Review 8.  Residual effects of hypnotics: epidemiology and clinical implications.

Authors:  Annemiek Vermeeren
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

9.  Prescription medicines and the risk of road traffic crashes: a French registry-based study.

Authors:  Ludivine Orriols; Bernard Delorme; Blandine Gadegbeku; Aurore Tricotel; Benjamin Contrand; Bernard Laumon; Louis-Rachid Salmi; Emmanuel Lagarde
Journal:  PLoS Med       Date:  2010-11-16       Impact factor: 11.069

Review 10.  The use of microcomputer-based psychomotor tests for the evaluation of benzodiazepine effects on human performance: a review with emphasis on temazepam.

Authors:  G W Kunsman; J E Manno; B R Manno; C M Kunsman; M A Przekop
Journal:  Br J Clin Pharmacol       Date:  1992-10       Impact factor: 4.335

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