Literature DB >> 17249

Prevalence of drugs among drivers arrested for drinking and driving in Finland.

A R Alha, M Karlsson, M Linnoila, I Lukkari.   

Abstract

A combined thin layer and gas chromatography system was developed for qualitative and quantitative analysis of drugs in biological samples after extraction with heptane-isoamyl alcohol. Both acidic and basic extraction procedures were used. Special methods were used for the extraction and detection of salicylates, isoniazid, and morphine. Particular attention was given to the detection of psychostimulants; though these drugs have seldom been found in drinking drivers in Finland they are commonly found in Sweden. Two percent of all suspected drinking drivers were also suspected of concommitant drug use, which led to primary sampling of urine. Of 100 such drivers, 24 had blood alcohol levels (BALs) which were negative and 18 of that 24 had drugs in their sample. Seventy-six of the 100 had positive BALs and 25 of the 76 had drugs in their samples. Of the randomly chosen 100 suspected drinking drivers, 5 had drugs in their samples, and 4 of these 5 had positive BALs. The benzodiazeomes were the most commonly detected drugs. No stimulants were found in our subjects.

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Year:  1977        PMID: 17249     DOI: 10.1007/BF00200498

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  13 in total

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Authors:  O PRIBILLA
Journal:  Arzneimittelforschung       Date:  1964-06

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Authors:  P TRINDER
Journal:  Biochem J       Date:  1954-06       Impact factor: 3.857

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Authors:  G Cimbura; J Kofoed
Journal:  J Chromatogr Sci       Date:  1974-05       Impact factor: 1.618

5.  Gas chromatographic determination of drugs in post-mortem blood.

Authors:  A Alha; T Korte
Journal:  Ann Med Exp Biol Fenn       Date:  1972

6.  Diazepam metabolism during chronic medication unbound fraction in plasma, erythrocytes and urine.

Authors:  I A Zingales
Journal:  J Chromatogr       Date:  1973-01-03

7.  A procedure for the rapid analysis of large numbers of urine samples for drugs.

Authors:  L R Goldbaum; P Santinga; A M Dominguez
Journal:  Clin Toxicol       Date:  1972       Impact factor: 4.467

8.  Determination of chlordiazepoxide plasma concentrations by electron capture gas-liquid chromatography.

Authors:  I A Zingales
Journal:  J Chromatogr       Date:  1971-10

9.  [Demonstration of centrally stimulating substances in pure form and after passage through the body by thin-layer chromatography].

Authors:  H Eberhardt; M Debackere
Journal:  Arzneimittelforschung       Date:  1965-08

10.  Fatal combined anileridine-pethidine poisoning. A gas chromatography, thin layer chromatography and mass spectrometry investigation.

Authors:  A Alha; M Karlsson; T Korte
Journal:  Z Rechtsmed       Date:  1975
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  3 in total

1.  [Role of drugs in traffic accidents. A pilot study of traffic accident offenders in Switzerland (Bern region)].

Authors:  L Ulrich; O Rudin; A Amsler; P Zink
Journal:  Z Rechtsmed       Date:  1984

2.  [Occurrence of diazepam in blood samples of drivers under the influence of alcohol (author's transl)].

Authors:  H P Gelbke; H J Schlicht; G Schmidt
Journal:  Z Rechtsmed       Date:  1978-01-31

3.  Role of drugs in traffic accidents.

Authors:  R Honkanen; L Ertama; M Linnoila; A Alha; I Lukkari; M Karlsson; O Kiviluoto; M Puro
Journal:  Br Med J       Date:  1980-11-15
  3 in total

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