Literature DB >> 7436592

Selective surgical management of cutaneous melanoma of the head and neck.

D F Roses, M N Harris, I Grunberger, S L Gumport.   

Abstract

A series of 206 patients with cutaneous melanoma of the head and neck has been studied. Ninety patients had a regional lymph node dissections performed. Seventeen lymph node dissections were done therapeutically and 73 were done electively. Thirty-one patients had histologically positive lymph nodes and, of these, 30 patients have been followed to the present time or death. Twenty-nine of these patients (97%) have developed systemic melanoma. Twenty-six patients have died and three are alive with disease. No patient had local recurrence alone while four had local recurrence synchronously with systemic metastases. This contrasts with 29 patients followed for greater than five years with histologically negative nodes, 27 (93.1%) of whom are alive with no evidence of recurrent disease. Regional node metastases with melanoma of the head and neck is an almost certain indication of systemic disease. A selective surgical approach to invasive melanoma in this region is proposed based on the observation in the 31 patients who had radical neck dissections with histologically positive nodes. The metastases always involved the nodal group adjacent to the primary site. This selective approach should allow optimal local control and accurate pathologic staging while limiting the extent of the surgery.

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Year:  1980        PMID: 7436592      PMCID: PMC1344944          DOI: 10.1097/00000658-198011000-00008

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  12 in total

1.  Clinicopathological correlations in a series of 117 malignant melanomas of the skin of adults.

Authors:  N LANE; R LATTES; J MALM
Journal:  Cancer       Date:  1958 Sep-Oct       Impact factor: 6.860

2.  Results of BCG adjuvant immunotherapy for melanoma of the head and neck.

Authors:  F R Eilber; C M Townsend; D L Morton
Journal:  Am J Surg       Date:  1976-10       Impact factor: 2.565

3.  Analysis of survival and disease control in stage I melanoma of the head and neck.

Authors:  F C Ames; E V Sugarbaker; A J Ballantyne
Journal:  Am J Surg       Date:  1976-10       Impact factor: 2.565

4.  Melanoma of the head and neck.

Authors:  M N Harris; D F Roses; A T Culliford; S L Gumport
Journal:  Ann Surg       Date:  1975-07       Impact factor: 12.969

5.  Results of regional lymph node dissection for melanoma.

Authors:  S L Gumport; M N Harris
Journal:  Ann Surg       Date:  1974-01       Impact factor: 12.969

6.  Malignant melanoma of the head and neck: a clinicopathological study.

Authors:  P J Fitzpatrick; T C Brown; J Reid
Journal:  Can J Surg       Date:  1972-03       Impact factor: 2.089

7.  Melanoma of the head and neck. A review of eighty-seven cases.

Authors:  C O Knutson; J M Hori; F R Watson
Journal:  Am J Surg       Date:  1972-10       Impact factor: 2.565

8.  Malignant melanoma of the head and neck.

Authors:  J N Simons
Journal:  Am J Surg       Date:  1972-10       Impact factor: 2.565

9.  Assessment of biopsy techniques and histopathologic interpretations of primary cutaneous malignant melanoma.

Authors:  D F Roses; A B Ackerman; M N Harris; G R Weinhouse; S L Gumport
Journal:  Ann Surg       Date:  1979-03       Impact factor: 12.969

10.  A multifactorial analysis of melanoma. II. Prognostic factors in patients with stage I (localized) melanoma.

Authors:  C M Balch; S J Soong; T M Murad; A L Ingalls; W A Maddox
Journal:  Surgery       Date:  1979-08       Impact factor: 3.982

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  3 in total

1.  Neck dissection for cutaneous malignant melanoma.

Authors:  C J O'Brien; M P Gianoutsos; M J Morgan
Journal:  World J Surg       Date:  1992 Mar-Apr       Impact factor: 3.352

2.  Local and in-transit metastases following definitive excision for primary cutaneous malignant melanoma.

Authors:  D F Roses; M N Harris; D Rigel; Z Carrey; R Friedman; A W Kopf
Journal:  Ann Surg       Date:  1983-07       Impact factor: 12.969

3.  Head and neck melanoma in 534 clinical Stage I patients. A prognostic factors analysis and results of surgical treatment.

Authors:  M M Urist; C M Balch; S J Soong; G W Milton; H M Shaw; V J McGovern; T M Murad; W H McCarthy; W A Maddox
Journal:  Ann Surg       Date:  1984-12       Impact factor: 12.969

  3 in total

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