Literature DB >> 7436558

Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis.

Z Balogh, A F El-Ghobarey, G S Fell, D H Brown, J Dunlop, W C Dick.   

Abstract

Total plasma zinc levels in patients with rheumatoid arthritis on different therapeutic treatments were determined in conjunction with total serum proteins, serum albumin and globulin, and articular index of joint tenderness, erythrocyte sedimentation rate, rheumatoid factor, serum copper, and serum iron. There were significantly lower zinc levels in patients with rheumatoid arthritis on nonsteroidal anti-inflammatory drugs than in patients on levamisole and penicillamine. Zinc levels correlated positively with serum albumin, and there was an inverse correlation between zinc levels and both ESR and globulin concentration in all rheumatoid patients. However, the correlation coefficient varied in the different treatment groups. The results of this study support the hypothesis that low plasma zinc level in rheumatoid arthritis is one of the nonspecific features of inflammation.

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Year:  1980        PMID： 7436558      PMCID： PMC1000551          DOI： 10.1136/ard.39.4.329

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  38 in total

1.  Characterization of the endogenous mediator(s) of serum zinc and iron depression during infection and other stresses.

Authors:  R S Pekarek; W R Beisel
Journal:  Proc Soc Exp Biol Med       Date:  1971-11

2.  Alleviation of the leg abnormality in zinc-deficient chicks by histamine and by various anti-arthritic agents.

Authors:  F H Nielsen; M L Sunde; W G Hoekstra
Journal:  J Nutr       Date:  1968-04       Impact factor: 4.798

3.  Rapid serum-zinc depletion associated with corticosteroid therapy.

Authors:  A Flynn; W J Pories; W H Strain; O A Hill; R B Fratianne
Journal:  Lancet       Date:  1971-11-27       Impact factor: 79.321

4.  Plasma-zinc in health and disease.

Authors:  J A Halsted; J C Smith
Journal:  Lancet       Date:  1970-02-14       Impact factor: 79.321

5.  Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis.

Authors:  D M Ritchie; J A Boyle; J M McInnes; M K Jasani; T G Dalakos; P Grieveson; W W Buchanan
Journal:  Q J Med       Date:  1968-07

6.  Effect of zinc deficiency on collagen metabolism.

Authors:  F Fernandez-Madrid; A S Prasad; D Oberleas
Journal:  J Lab Clin Med       Date:  1971-11

7.  Binding of zinc to amino acids and serum proteins in vitro.

Authors:  A S Prasad; D Oberleas
Journal:  J Lab Clin Med       Date:  1970-09

8.  The effect of chrysotherapy on trace metals in patients with rheumatoid arthritis.

Authors:  W Niedermeier; W W Prillaman; J H Griggs
Journal:  Arthritis Rheum       Date:  1971 Jul-Aug

9.  Comparative metabolism of copper and zinc in patients with Wilson's disease (hepatolenticular degeneration).

Authors:  J T McCall; N P Goldstein; R V Randall; J B Gross
Journal:  Am J Med Sci       Date:  1967-07       Impact factor: 2.378

10.  The computed distribution of copper(II) and zinc(II) ions among seventeen amino acids present in human blood plasma.

Authors:  P S Hallman; D D Perrin; A E Watt
Journal:  Biochem J       Date:  1971-02       Impact factor: 3.857
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  11 in total

1.  A pilot study on zinc levels in patients with rheumatoid arthritis.

Authors:  Artur Mierzecki; Dorota Strecker; Krystyna Radomska
Journal:  Biol Trace Elem Res       Date:  2011-01-29       Impact factor: 3.738

2.  Effects of acute and chronic prednisolone treatment on serum zinc levels in rats with adjuvant arthritis.

Authors:  J Fontaine; J Nève; A Peretz; P Capel; J P Famaey
Journal:  Agents Actions       Date:  1991-07

3.  Predictive clinical and laboratory parameters for serum zinc and copper in rheumatoid arthritis.

Authors:  H Mussalo-Rauhamaa; Y T Konttinen; J Lehto; V Honkanen
Journal:  Ann Rheum Dis       Date:  1988-10       Impact factor: 19.103

4.  Another look at zinc.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-04-04

5.  Reduced zinc in peripheral blood cells from patients with inflammatory connective tissue diseases.

Authors:  K L Svenson; R Hällgren; E Johansson; U Lindh
Journal:  Inflammation       Date:  1985-06       Impact factor: 4.092

Review 6.  Copper and zinc body levels in inflammation: an overview of the data obtained from animal and human studies.

Authors:  R Milanino; M Marrella; R Gasperini; M Pasqualicchio; G Velo
Journal:  Agents Actions       Date:  1993-07

7.  Changes in zinc, copper and selenium status during adjuvant-induced arthritis in rats.

Authors:  J Nève; J Fontaine; A Peretz; J P Famaey
Journal:  Agents Actions       Date:  1988-08

8.  Nutritional status in patients with rheumatoid arthritis.

Authors:  M Helliwell; E J Coombes; B J Moody; G F Batstone; J C Robertson
Journal:  Ann Rheum Dis       Date:  1984-06       Impact factor: 19.103

9.  Serum trace elements in juvenile chronic arthritis.

Authors:  V Honkanen; P Pelkonen; H Mussalo-Rauhamaa; J Lehto; T Westermarck
Journal:  Clin Rheumatol       Date:  1989-03       Impact factor: 2.980

10.  Zinc sulphate in rheumatoid arthritis.

Authors:  P C Mattingly; A G Mowat
Journal:  Ann Rheum Dis       Date:  1982-10       Impact factor: 19.103
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