Literature DB >> 21279466

A pilot study on zinc levels in patients with rheumatoid arthritis.

Artur Mierzecki1, Dorota Strecker, Krystyna Radomska.   

Abstract

The aim of the study was to evaluate zinc levels in three biological compartments (serum, erythrocytes and hair) in patients with rheumatoid arthritis (RA) as compared to healthy individuals. Zinc levels in serum, erythrocytes and hair (in 74 patients with RA and 30 healthy individuals) were assessed by atomic absorption spectroscopy. The mean hair zinc content was significantly lower in RA patients as compared to healthy individuals (p<0.001). Moreover, a positive correlation was observed in the RA patient group between the erythrocyte zinc levels and the prednisone dose (rs=0.48, p<0.05), and a negative correlation was found in this population between the serum zinc levels and disease duration (rs=-0.42, p<0.0006). In conclusion, it seems that hair may be a useful complementary study material for evaluating "zinc status" in rheumatoid arthritis patients.

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Year:  2011        PMID: 21279466      PMCID: PMC3187853          DOI: 10.1007/s12011-010-8952-2

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  21 in total

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4.  Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis.

Authors:  Kristen T Crowell; Shannon L Kelleher; David I Soybel; Charles H Lang
Journal:  Physiol Rep       Date:  2016-11

Review 5.  Zinc Status and Autoimmunity: A Systematic Review and Meta-Analysis.

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Journal:  Nutrients       Date:  2018-01-11       Impact factor: 5.717

6.  ZIP8 exacerbates collagen-induced arthritis by increasing pathogenic T cell responses.

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  6 in total

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