Literature DB >> 74364

Ultrastructure of isolated human mast cells during histamine release induced by ionophore A 23187.

H Behrendt, U Rosenkranz, W Schmutzler.   

Abstract

In the presence of calcium, the ionophore A 23187 (10(-7) TO 10(-6) M) causes a dose-dependent histamine release from isolated human mast cells. The accompanying degranulation process is characterized by a formation of channels of fused mast cell granules and by an exocytotic extrusion of altered granule material. Simultaneously, large numbers of newly formed 70 A filaments occur. These filaments probably have a key function in secreting human mast cells.

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Year:  1978        PMID： 74364     DOI： 10.1159/000232022

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN： 0020-5915


  9 in total

1.  Intracellular adenosine inhibits IgE-dependent degranulation of human skin mast cells.

Authors:  Gregorio Gomez; Vincent Nardone; Sahar Lotfi-Emran; Wei Zhao; Lawrence B Schwartz
Journal:  J Clin Immunol       Date:  2013-11       Impact factor: 8.317

Review 2.  Beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells.

Authors:  Noel M Rysavy; Lori M N Shimoda; Alyssa M Dixon; Mark Speck; Alexander J Stokes; Helen Turner; Eric Y Umemoto
Journal:  Bioarchitecture       Date:  2014

3.  The effects of the anaphylatoxins C3a and C5a on isolated mast cells from rat and man.

Authors:  H Jürgensen; H Behrendt; B Damerau; W Schmutzler
Journal:  Agents Actions       Date:  1986-04

4.  Cultures of mast cell-like (MCL) cells from human pleural exudate cells.

Authors:  G Krüger; W Sterry; B M Czarnetzki
Journal:  Blut       Date:  1983-03

5.  On the isolation of mast cells from human adenoids and tonsils.

Authors:  N Grosman; C Hjort-Sørensen; S M Jensen
Journal:  Agents Actions       Date:  1987-04

6.  Recognition of the 'calcium paradox' and the effects of verapamil and gallopamil in human adenoidal mast cells.

Authors:  D Eichelberg; R Peters; W Schmutzler
Journal:  Agents Actions       Date:  1984-04

7.  Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation.

Authors:  A M Dvorak; I Hammel; E S Schulman; S P Peters; D W MacGlashan; R P Schleimer; H H Newball; K Pyne; H F Dvorak; L M Lichtenstein
Journal:  J Cell Biol       Date:  1984-11       Impact factor: 10.539

8.  Secretion in dissociated human pulmonary mast cells. Evidence for solubilization of granule contents before discharge.

Authors:  J P Caulfield; R A Lewis; A Hein; K F Austen
Journal:  J Cell Biol       Date:  1980-05       Impact factor: 10.539

Review 9.  Mast cell mediators: their differential release and the secretory pathways involved.

Authors:  Tae Chul Moon; A Dean Befus; Marianna Kulka
Journal:  Front Immunol       Date:  2014-11-14       Impact factor: 7.561
  9 in total

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