Literature DB >> 2425572

The effects of the anaphylatoxins C3a and C5a on isolated mast cells from rat and man.

H Jürgensen, H Behrendt, B Damerau, W Schmutzler.   

Abstract

Of the complement peptides comprising anaphylatoxin activity, only C5a caused a very small (less than 1.5%) but statistically significant histamine release from isolated human adenoidal mast cells. C3a and the respective des-Arg-derivatives were found to be ineffective. In rat peritoneal mast cells, neither peptide caused histamine release.

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Year:  1986        PMID： 2425572     DOI： 10.1007/bf01988008

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  7 in total

1.  Modification of the enzymatic isotopic assay of histamine and its application to measurement of histamine in tissues, serum and urine.

Authors:  M A Beaven; S Jacobsen; Z Horáková
Journal:  Clin Chim Acta       Date:  1972-03       Impact factor: 3.786

2.  Structural elements of anaphylatoxin obtained by contact activation of hog serum.

Authors:  M Liefländer; D Dielenberg; G Schmidt; W Vogi
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-03

3.  Complement-induced histamine release from human basophils. I. Generation of activity in human serum.

Authors:  W A Hook; R P Siraganian; S M Wahl
Journal:  J Immunol       Date:  1975-04       Impact factor: 5.422

4.  Release of histamine from rat mast cells by the complement peptides C3a and C5a.

Authors:  A R Johnson; T E Hugli; H J Müller-Eberhard
Journal:  Immunology       Date:  1975-06       Impact factor: 7.397

5.  Ultrastructure of isolated human mast cells during histamine release induced by ionophore A 23187.

Authors:  H Behrendt; U Rosenkranz; W Schmutzler
Journal:  Int Arch Allergy Appl Immunol       Date:  1978

6.  C5a-induced histamine release. Species specificity.

Authors:  J F Regal; T M Hardy; F B Casey; L W Chakrin
Journal:  Int Arch Allergy Appl Immunol       Date:  1983

7.  Recognition of the 'calcium paradox' and the effects of verapamil and gallopamil in human adenoidal mast cells.

Authors:  D Eichelberg; R Peters; W Schmutzler
Journal:  Agents Actions       Date:  1984-04
  7 in total

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