Literature DB >> 7434002

Anesthetics as teratogens: nitrous oxide is fetotoxic, xenon is not.

G A Lane, M L Nahrwold, A R Tait, M Taylor-Busch, P J Cohen, A R Beaudoin.   

Abstract

Exposure of pregnant rats to the anesthetic nitrous oxide on the ninth day of gestation causes fetal resorption, skeletal anomalies, and macroscopic lesions including encephalocele, anophthalmia, microphthalmia, and gastroschisis. The inert gas xenon, which has anesthetic properties similar to those of nitrous oxide, does not cause teratogenic effects under the same experimental conditions.

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Year:  1980        PMID: 7434002     DOI: 10.1126/science.7434002

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  16 in total

Review 1.  Xenon anaesthesia.

Authors:  T Marx; M Schmidt; U Schirmer; H Reinelt
Journal:  J R Soc Med       Date:  2000-10       Impact factor: 5.344

Review 2.  Animal models in pediatric surgery.

Authors:  A Mortell; S Montedonico; P Puri
Journal:  Pediatr Surg Int       Date:  2005-12-06       Impact factor: 1.827

3.  Thoracic paravertebral block for breast surgery in a pregnant woman -A case report-.

Authors:  Sang Il Park; Yoon-Hee Kim; Kyu Cheol Han; Sun Yeul Lee; Ann Misun Youn; Seok Hwa Yoon; Youn Hee Choi
Journal:  Korean J Anesthesiol       Date:  2010-12-31

Review 4.  Teratogens inducing congenital abdominal wall defects in animal models.

Authors:  Dennis R Van Dorp; John M Malleis; Brian P Sullivan; Michael D Klein
Journal:  Pediatr Surg Int       Date:  2009-09-16       Impact factor: 1.827

5.  Xenon is another laughing gas.

Authors:  T Kawaguchi; T Mashimo; M Yagi; E Takeyama; I Yoshiya
Journal:  Can J Anaesth       Date:  1996-06       Impact factor: 5.063

Review 6.  Waste anesthetic gas exposure and strategies for solution.

Authors:  Hai-Bo Deng; Feng-Xian Li; Ye-Hua Cai; Shi-Yuan Xu
Journal:  J Anesth       Date:  2018-02-05       Impact factor: 2.078

7.  Health effects associated with exposure to anaesthetic gases in Ontario hospital personnel.

Authors:  S S Guirguis; P L Pelmear; M L Roy; L Wong
Journal:  Br J Ind Med       Date:  1990-07

Review 8.  Adverse effects of nitrous oxide.

Authors:  J B Brodsky; E N Cohen
Journal:  Med Toxicol       Date:  1986 Sep-Oct

9.  Monitoring xenon in the breathing circuit with a thermal conductivity sensor. Comparison with a mass spectrometer and implications on monitoring other gases.

Authors:  Martin Luginbühl; Rolf Lauber; Peter Feigenwinter; Alex M Zbinden
Journal:  J Clin Monit Comput       Date:  2002-01       Impact factor: 2.502

Review 10.  Health hazards and nitrous oxide: a time for reappraisal.

Authors:  J A Yagiela
Journal:  Anesth Prog       Date:  1991 Jan-Feb
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