| Literature DB >> 7426832 |
Abstract
In the presence of guanethidine, periarterial nerve stimulation caused a frequency-dependent motor response in the rabbit isolated ileum. Tachyphylaxis to capsaicin greatly diminished the effect of periarterial stimulation; the remaining portion of the contractile response was susceptible to hexamethonium. The motor effect of periarterial stimulation is mediated by two different mechanisms: one via parasympathetic preganglionic nerves and the other sensitive to capsaicin.Entities:
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Year: 1980 PMID: 7426832 PMCID: PMC2044320 DOI: 10.1111/j.1476-5381.1980.tb07924.x
Source DB: PubMed Journal: Br J Pharmacol ISSN: 0007-1188 Impact factor: 8.739