Literature DB >> 742553

Stimulation of gastric acid secretion by dimaprit in unanesthetized rats.

H Petersen, M I Grossman.   

Abstract

In unanesthetized rats, dimaprit and histamine given by intravenous infusion were about equipotent in stimulating gastric acid secretion. The maximal rate of acid secretion in response to dimaprit was significantly greater than to histamine but not significantly different from the response to pentagastrin.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 742553     DOI： 10.1007/bf01998883

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  4 in total

1.  Response of rats with gastric fistulas to injection of gastrin.

Authors:  K ADASHEK; M I GROSSMAN
Journal:  Proc Soc Exp Biol Med       Date:  1963-03

2.  Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology.

Authors:  M E Parsons; D A Owen; C R Ganellin; G J Durant
Journal:  Agents Actions       Date:  1977-03

3.  What do you do with basal in dose-response studies? A suggested answer.

Authors:  M I Grossman
Journal:  Gastroenterology       Date:  1973-08       Impact factor: 22.682

4.  Effect of dimaprit on gastric acid secretion in conscious cats.

Authors:  D C Carter; M Impicciatore; M I Grossman
Journal:  Agents Actions       Date:  1978-10
  4 in total
  5 in total

Review 1.  Gastrin-histamine sequence in the regulation of gastric acid secretion.

Authors:  H L Waldum; A K Sandvik; E Brenna; H Petersen
Journal:  Gut       Date:  1991-06       Impact factor: 23.059

2.  Gastrointestinal ulceration in the guinea pig in response to dimaprit, histamine, and H1- and H2-blocking agents.

Authors:  C H Cho; C J Pfeiffer
Journal:  Dig Dis Sci       Date:  1981-04       Impact factor: 3.199

3.  Conversion and pharmacokinetics profiles of a novel pro-drug of 3-n-butylphthalide, potassium 2-(1-hydroxypentyl)-benzoate, in rats and dogs.

Authors:  Jiang Li; Shao-Feng Xu; Ying Peng; Nan Feng; Ling Wang; Xiao-Liang Wang
Journal:  Acta Pharmacol Sin       Date:  2017-09-14       Impact factor: 6.150

4.  Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.

Authors:  P Del Soldato
Journal:  Agents Actions       Date:  1984-02

5.  Pharmacokinetics of a novel antiarrhythmic drug, actisomide.

Authors:  C S Cook; L F Rozek; J Stolzenbach; S Anderson; G L Schoenhard; A Karim
Journal:  Pharm Res       Date:  1993-03       Impact factor: 4.200
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.