Literature DB >> 7418807

Effects of bicuculline and chlordiazepoxide on locomotor activity and avoidance performance in rats.

V Cuomo, I Cortese.   

Abstract

Bicuculline, at a dose of 1 mg/kg which, per se, failed to change locomotor activity in rats, counteracts the facilitating effect induced by chlordiazepoxide (10 mg/kg). Conversely, bicuculline (1 mg/kg) does not modify the decrease of motor activity and the disruption of avoidance performance induced by this benzodiazepine derivative (20 mg/kg).

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Year:  1980        PMID： 7418807     DOI： 10.1007/bf01976133

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  [The action of nicotine on conditioning to the avoidance reaction in the rat].

Authors:  D BOVET; G BIGNAMI; F ROBUSTELLI
Journal:  C R Hebd Seances Acad Sci       Date:  1963-01-14

2.  Antagonism of diazepam against central anticholinergic drug-induced hyperactivity in mice: involvement of a GABA mechanism.

Authors:  P Soubrié; P Simon; J R Boissier
Journal:  Neuropharmacology       Date:  1976-12       Impact factor: 5.250

3.  Effects of chlordiazepoxide, CNS stimulants and their combinations on avoidance behaviour in mice.

Authors:  M Sansone
Journal:  Arch Int Pharmacodyn Ther       Date:  1975-06

4.  Further evidence for GABA-ergic mechanisms in the action of benzodiazepines.

Authors:  V V Zakusov; R U Ostrovskaya; S N Kozhechkin; V V Markovich; G M Molodavkin; T A Voronina
Journal:  Arch Int Pharmacodyn Ther       Date:  1977-10

5.  Drug-induced modifications of discriminated avoidance behavior in rats.

Authors:  C Morpurgo
Journal:  Psychopharmacologia       Date:  1965-07-28

6.  Genotype-dependent sensitivity and tolerance to morphine and heroin: dissociation between opiate-induced running and analgesia in the mouse.

Authors:  A Oliverio; C Castellano
Journal:  Psychopharmacologia       Date:  1974

7.  Comparative study of the antagonism of bemegride and picrotoxin on behavioural depressant effects of diazepam in rats and mice.

Authors:  P Soubrie; P Simon
Journal:  Neuropharmacology       Date:  1978-02       Impact factor: 5.250

8.  Effects of centrally acting drugs on exploratory behaviour in rats.

Authors:  A S Marriott; P S Spencer
Journal:  Br J Pharmacol Chemother       Date:  1965-10

9.  Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized mice.

Authors:  M Sansone
Journal:  Psychopharmacology (Berl)       Date:  1978-10-31       Impact factor: 4.530

10.  Effects of P-chlorophenylalanine (PCPA) on avoidance conditioning in guinea pigs.

Authors:  V Cuomo; A Marino
Journal:  Pharmacol Res Commun       Date:  1974-12
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  4 in total

1.  Behavioural responsiveness to muscimol and apomorphine 2 months after prolonged treatment with estradiol in rats.

Authors:  V Cuomo; R Cagiano; J Apud; C Masotto; G Racagni
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

2.  Behavioural and biochemical effects in the adult rat after prolonged postnatal administration of clozapine.

Authors:  V Cuomo; R Cagiano; I Mocchetti; E Coen; F Cattabeni; G Racagni
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

3.  Biochemical and behavioral changes in rats after prolonged treatment with desipramine: interaction with p-chlorophenylalanine.

Authors:  N Brunello; A Volterra; R Cagiano; G C Ianieri; V Cuomo; G Racagni
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-10       Impact factor: 3.000

4.  Early postnatal chlordiazepoxide administration: permanent behavioural effects in the mature rat and possible involvement of the GABA-benzodiazepine system.

Authors:  E Coen; M P Abbracchio; W Balduini; R Cagiano; V Cuomo; G Lombardelli; G Peruzzi; M C Ragusa; F Cattabeni
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
  4 in total

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