Literature DB >> 7416795

Pharmacokinetic and clinical comparison of two 8-methoxypsoralen brands.

K E Andersen, T Menne, M Gammeltoft, N Hjorth, E Larsen, P Solgaard.   

Abstract

We compared the Danish 8-MOP brand Meladinine with the Austrial brand Oxsoralen because of our discouraging result with PUVA in treating psoriasis. Nine healthy volunteers participated in the investigation. The plasma level of 8-MOP was measured by a gas chromatogrpahic-mass spectrometric method using isotopic dilution technique. The level obtained with Oxsoralen was on the average 5.8 times higher than that with Meladinine.

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Year:  1980        PMID： 7416795     DOI： 10.1007/bf00403883

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  11 in total

1.  Difference in the efficiency of two delivery forms of 8-methoxypsoralen.

Authors:  M K Polano; A A Schothorst
Journal:  Dermatologica       Date:  1977

2.  Phototesting and dosimetry for photochemotherapy.

Authors:  K Wolff; F Gschnait; H Hönigsmann; K Konrad; J A Parrish; T B Fitzpatrick
Journal:  Br J Dermatol       Date:  1977-01       Impact factor: 9.302

3.  Photoinactivation of skin fibroblasts by fractionated treatment with 8-methoxypsoralen and UVA.

Authors:  J Pohl; E Christophers
Journal:  J Invest Dermatol       Date:  1979-08       Impact factor: 8.551

4.  PUVA: a review of ultraviolet dosimetry.

Authors:  B L Diffey
Journal:  Br J Dermatol       Date:  1978-06       Impact factor: 9.302

5.  The qualitative and quantitative analysis of 8-methoxypsoralen by HPLC-UV and GLC-MS.

Authors:  C N Hensby
Journal:  Clin Exp Dermatol       Date:  1978-12       Impact factor: 3.470

6.  Rapid, sensitive gas chromatographic analysis of 8-methoxypsoralen in human plasma.

Authors:  J Schmid; F W Koss
Journal:  J Chromatogr       Date:  1978-11-01

7.  Determination of 8-methoxypsoralen in plasma by electron capture gas chromatography.

Authors:  H Ehrsson; S Eksborg; I Wallin; N Kållberg; G Swanbeck
Journal:  J Chromatogr       Date:  1977-10-11

8.  Photochemotherapy for psoriasis with orally administered methoxsalen.

Authors:  K W Wolff; T B Fitzpatrick; J A Parrish; F Gschnait; B Gilchrest; H Hönigsmann; M A Pathak; L Tannenbaum
Journal:  Arch Dermatol       Date:  1976-07

9.  Plasma levels of 8-methoxypsoralen and phototoxicity studies during PUVA treatment of psoriasis with meladinin tablets.

Authors:  P Thune
Journal:  Acta Derm Venereol       Date:  1978       Impact factor: 4.437

10.  Photochemotherapy of psoriasis with relevance to 8-methoxypsoralen plasma level and low intensity irradiation.

Authors:  P Thune; G Volden
Journal:  Acta Derm Venereol       Date:  1977       Impact factor: 4.437
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  5 in total

1.  [8-Methoxypsoralen (8-MOP)-a new galenic form and its relation to 8-MOP serum levels (author's transl)].

Authors:  V Nitsche; M Raff; H Bardach
Journal:  Arch Dermatol Res       Date:  1981       Impact factor: 3.017

2.  Difference in bioavailability between two brands of 8-methoxypsoralen and its impact on the clinical response in psoriatic patients.

Authors:  M J Herfst; F A De Wolff
Journal:  Br J Clin Pharmacol       Date:  1982-04       Impact factor: 4.335

3.  Intraindividual variations of 8-methoxypsoralen plasma levels.

Authors:  M Schäfer-Korting; H C Korting
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

4.  Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.

Authors:  H C Korting; M Schäfer-Korting; E Roser-Maass; E Mutschler
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

Review 5.  Clinical pharmacokinetics of methoxsalen and other psoralens.

Authors:  F A de Wolff; T V Thomas
Journal:  Clin Pharmacokinet       Date:  1986 Jan-Feb       Impact factor: 6.447
  5 in total

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