Primary malignant mixed tumors of the lacrimal gland. Report of 10 cases.

Ten consecutive cases of malignant mixed tumor (pleomorphic adenocarcinoma) primary in the lacrimal gland were studied for clinical features, pathology, course and prognosis and surgical management. Long-term follow-up data were available on all patients and emphasized the varied nature of the neoplasm. Survival intervals after the initial operation varied and seemed dependent on whether the neoplasm was initially histologically malignant or became malignant during the recurrence of a benign mixed tumor. An en bloc, one-stage removal of neoplasm with attached periorbita and underlying bone is recommended to minimize early dissemination via bone.