Literature DB >> 7406868

The detection of messenger ribonucleic acid sequences in heterogeneous nuclear ribonucleic acid fractions of the oestrogen-stimulated rat uterus.

S Aziz, J T Knowler.   

Abstract

cDNA (complementary DNA) complementary to the abundant sequences of mRNA isolated from oestrogen-stimulated uterus was hybridized to polyadenylated and non-polyadenylated uterine hnRNA (heterogeneous nuclear RNA). High-molecular-weight polyadenylated hnRNA, isolated under denaturing conditions, was able to saturate the cDNA, but complementary sequences were low abundance when compared with homologous mRNA. The mRNA sequence content of the polyadenylated hnRNA increased considerably during oestrogen-induced growth of the uterus. Non-polyadenylated hnRNA also contained sequences complementary to the cDNA.

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Year:  1980        PMID： 7406868      PMCID： PMC1162519          DOI： 10.1042/bj1870265

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  10 in total

1.  Regulation of polyribosome formation and protein synthesis in the uterus. Effect of ovariectomy and administration of oestradiol-17beta on the amino acid-incorporation activity in vitro and the cytoplasmic concentration in vivo of polyribosomal preparation.

Authors:  C S Teng; T H Hamilton
Journal:  Biochem J       Date:  1967-12       Impact factor: 3.857

Review 2.  Relationship between the estrogen induced protein ip and other parameters of estrogenic stimulation. A hypothesis.

Authors:  P Galand; L Flandroy; N Mairesse
Journal:  Life Sci       Date:  1978-01       Impact factor: 5.037

3.  The oestrogen-stimulated synthesis of heterogeneous nuclear ribonucleic acid in the uterus of immature rats.

Authors:  J T Knowler; R M Smellie
Journal:  Biochem J       Date:  1973-04       Impact factor: 3.857

4.  Characterization of uterine heterogeneous nuclear ribonucleic acid and the effect of oestradiol-17 beta on its synthesis.

Authors:  S Aziz; J T Knowler
Journal:  Biochem J       Date:  1978-06-15       Impact factor: 3.857

5.  The effects of oestradiol-17beta on the ribonucleic acid polymerases of immature rabbit uterus.

Authors:  N M Borthwick; R M Smellie
Journal:  Biochem J       Date:  1975-04       Impact factor: 3.857

6.  Diversity and complexity of uterine mRNA from rats of differing hormonal states.

Authors:  S Aziz; A Balmain; J T Knowler
Journal:  Eur J Biochem       Date:  1979-10

7.  Qualitative and quantitative changes in uterine mRNA populations in response to oestradiol treatment of rats.

Authors:  S Aziz; A Balmain; J T Knowler
Journal:  Eur J Biochem       Date:  1979-10

8.  Early estrogen action: stimulation of the metabolism of high molecular weight and ribosomal RNAs (estradiol-17 -RNA isolation-uterus-ribosomal RNA precursors-actinomycin D).

Authors:  D N Luck; T H Hamilton
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

9.  The kinetics of the incorporation of newly synthesized ribonucleic acid and protein into the ribosomes of the uterus of the oestrogen-stimulated immature rat.

Authors:  M J Merryweather; J T Knowler
Journal:  Biochem J       Date:  1980-02-15       Impact factor: 3.857

10.  The synthesis of ribonucleic acid in immature rat uterus responding to oestradiol-17 beta.

Authors:  J T Knowler; R M Smellie
Journal:  Biochem J       Date:  1971-11       Impact factor: 3.857
  10 in total

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