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Literature DB >> 687360

Characterization of uterine heterogeneous nuclear ribonucleic acid and the effect of oestradiol-17 beta on its synthesis.

Abstract

An early response to the administration of oestradiol-17 beta to immature rats is a dramatic stimulation in the synthesis of uterine hnRNA (heterogenous nuclear RNA). High-molecular-weight fractions of the hnRNA were purified and subfractionated on poly(U)-Sepharose into fractions that differed in their poly(A) content and their size profile on polyacrylamide gels. Oestrogen treatment of the rats stimulated the synthesis of all three fractions of high-molecular-weight hnRNA, but the kinetics of synthesis, degree of stimulation and size distribution of the newly synthesize RNA differed in each fraction.

Entities: Chemical Species

Mesh：

Substances：
Estradiol
RNA

Year: 1978 PMID： 687360 PMCID： PMC1185734 DOI： 10.1042/bj1720587

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

27 in total

6. Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA.

Authors: W Jelinek; M Adesnik; M Salditt; D Sheiness; R Wall; G Molloy; L Philipson; J E Darnell
Journal: J Mol Biol Date: 1973-04-15 Impact factor: 5.469

10. Translation of Xenopus liver messenger RNA in Xenopus oocytes: vitellogenin synthesis and conversion to yolk platelet proteins.

Authors: M V Berridge; C D Lane
Journal: Cell Date: 1976-06 Impact factor: 41.582

3 in total

1. The detection of messenger ribonucleic acid sequences in heterogeneous nuclear ribonucleic acid fractions of the oestrogen-stimulated rat uterus.

Authors: S Aziz; J T Knowler
Journal: Biochem J Date: 1980-04-01 Impact factor: 3.857

2. Changes in polyribosomes and poly(A)-containing polyribosomal RNA in the uterus of the ovariectomized rat in response to oestradiol-17 beta treatment.

Authors: P J Pretorius; C J Reinecke
Journal: Biochem J Date: 1980-06-15 Impact factor: 3.857

3. The kinetics of the incorporation of newly synthesized ribonucleic acid and protein into the ribosomes of the uterus of the oestrogen-stimulated immature rat.

Authors: M J Merryweather; J T Knowler
Journal: Biochem J Date: 1980-02-15 Impact factor: 3.857

3 in total

Characterization of uterine heterogeneous nuclear ribonucleic acid and the effect of oestradiol-17 beta on its synthesis.

1. A precursor of globin messenger RNA.

2. Effects of oestradiol-17beta on the synthesis of uterine heterogeneous nuclear ribonucleic acid [proceedings].

3. Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells.

4. The role of protein in the estrogen-stimulated in vitro RNA synthesis of isolated rat uterine nucleoli.

5. Purification of messenger RNA and heterogeneous nuclear RNA containing poly(a) sequences.

6. Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA.

7. Polyadenylic acid segment in mRNA becomes shorter with age.

8. Possible involvement of nuclear DNA-like RNA in the control of ribosomal RNA synthesis.

9. The effects of oestradiol-17beta on the ribonucleic acid polymerases of immature rabbit uterus.

10. Translation of Xenopus liver messenger RNA in Xenopus oocytes: vitellogenin synthesis and conversion to yolk platelet proteins.

1. The detection of messenger ribonucleic acid sequences in heterogeneous nuclear ribonucleic acid fractions of the oestrogen-stimulated rat uterus.

2. Changes in polyribosomes and poly(A)-containing polyribosomal RNA in the uterus of the ovariectomized rat in response to oestradiol-17 beta treatment.

3. The kinetics of the incorporation of newly synthesized ribonucleic acid and protein into the ribosomes of the uterus of the oestrogen-stimulated immature rat.