Literature DB >> 7403876

Gastrin injected into the lateral hypothalamus stimulates secretion of gastric acid in rats.

B L Tepperman, M D Evered.   

Abstract

Intrahypothalamic injections of 100 picomoles of pentagastrin or natural gastrin promptly increased secretion of gastric acid in conscious rats. The response was blocked by atropine and by vagotomy. The same doses, injected intravenously or into other forebrain sites, did not increase secretion, nor did intrahypothalamic injections of other peptides common to the gut and brain.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7403876     DOI： 10.1126/science.7403876

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Neurobiologic and psychobiologic mechanisms in gastric function and ulceration.

Authors:  H Weiner; D Novin; C V Grijalva; Y Taché; T Garrick
Journal:  West J Med       Date:  1985-08

2.  Pentagastrin modulation of sensitivity of neurons of the lateral hypothalamus to noradrenaline and dopamine.

Authors:  E V Borisova; M Filipp
Journal:  Neurosci Behav Physiol       Date:  1990 Nov-Dec

3.  Neural discharge can be modulated by carotid arterial injection of gastrin-17 in rat hypothalamic paraventricular nucleus.

Authors:  T Sakaguchi; N Sandoh
Journal:  Experientia       Date:  1995-08-16

4.  Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption.

Authors:  Theresa Berndt; Leslie F Thomas; Theodore A Craig; Stacy Sommer; Xujian Li; Eric J Bergstralh; Rajiv Kumar
Journal:  Proc Natl Acad Sci U S A       Date:  2007-06-12       Impact factor: 11.205

5.  Influence of dopamine receptor agonists on gastric acid secretion induced by intraventricular administration of thyrotropin-releasing hormone in the perfused stomach of anaesthetized rats.

Authors:  M Maeda-Hagiwara; K Watanabe
Journal:  Br J Pharmacol       Date:  1983-05       Impact factor: 8.739
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.