Literature DB >> 740127

Increase of ornithine decarboxylase activity elicited by reserpine in the peripheral and central monoaminergic systems of the rat.

K Deckardt, J F Pujol, M F Belin, N Seiler, M Jouvet.   

Abstract

Ornithine decarboxylase activity was increased about tenfold in adrenal glands and in brain regions preponderantly containing aminergic neurons, by a single dose of 16 mumol/kg of reserpine. Maximal enzyme activity in the adrenal glands was observed at about 8 hr after reserpine administration. The ornithine decarboxylase activity-time curves in the brain regions showed a concomitant polyphasic course, with the highest maximum at 12 hr postinjection. Ornithine decarboxylase induction is discussed as an early event in the cascade of molecular events preceding the induction of cell typic enzymes.

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Year:  1978        PMID： 740127     DOI： 10.1007/bf00965997

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  27 in total

1.  Diurnal variations in activity of four pyridoxal enzymes in rat liver during metabolic transition from high carbohydrate to high protein diet.

Authors:  S Yanagl; H A Campbell; V R Potter
Journal:  Life Sci       Date:  1975-11-01       Impact factor: 5.037

2.  Regional distribution of putrescine, spermidine and spermine in relation to the distribution of RNA and DNA in the rat nervous system.

Authors:  N Seiler; T Schmidt-Glenewinkel
Journal:  J Neurochem       Date:  1975-04       Impact factor: 5.372

3.  Differential rates of increase in pontine tyrosine hydroxylase and dopamine-beta-hydroxylase activities after reserpine.

Authors:  S M Brooke; H C Fibiger
Journal:  Brain Res       Date:  1975-03-07       Impact factor: 3.252

4.  Adenosine cyclic 3',5'-monophosphate-dependent protein kinase and ornithine decarboxylase involvement in the induction of cytochrome P-450 and hepatic hypertrophy.

Authors:  M Costa; E R Costa; C A Manen; I G Sipes; D H Russell
Journal:  Mol Pharmacol       Date:  1976-09       Impact factor: 4.436

5.  Induction of ornithine decarboxylase in glioma and neuroblastoma cells.

Authors:  U Bachrach
Journal:  FEBS Lett       Date:  1976-09-15       Impact factor: 4.124

Review 6.  New aspects of polyamine biosynthesis in eukaryotic organisms.

Authors:  H G Williams-Ashman; J Jänne; G L Coppoc; M E Geroch; A Schenone
Journal:  Adv Enzyme Regul       Date:  1972

7.  Effects of methyl xanthine derivatives on cyclic AMP levels and ornithine decarboxylase activity of rat tissues.

Authors:  C V Byus; D H Russell
Journal:  Life Sci       Date:  1974-12-01       Impact factor: 5.037

8.  Involvement of adenosine 3',5'-monophosphate in the activation of tyrosine hydroxylase elicited by drugs.

Authors:  A Guidotti; E Costa
Journal:  Science       Date:  1973-03-02       Impact factor: 47.728

9.  Increased tyrosine hydroxylase activity in the locus coeruleus of rat brain stem after reserpine treatment and cold stress.

Authors:  R E Zigmond; F Schon; L L Iversen
Journal:  Brain Res       Date:  1974-04-26       Impact factor: 3.252

10.  Reserpine selectively increases tyrosine hydroxylase and dopamine-beta-hydroxylase enzyme protein in central noradrenergic neurons.

Authors:  D J Reis; T H Joh; R A Ross; V M Pickel
Journal:  Brain Res       Date:  1974-12-06       Impact factor: 3.252
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  2 in total

1.  Regulatory interrelations between GABA and polyamines. I. Brain GABA levels and polyamine metabolism.

Authors:  N Seiler; G Bink; J Grove
Journal:  Neurochem Res       Date:  1979-08       Impact factor: 3.996

Review 2.  Implication of the polyamine system in mental disorders.

Authors:  Laura M Fiori; Gustavo Turecki
Journal:  J Psychiatry Neurosci       Date:  2008-03       Impact factor: 6.186
  2 in total

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