Literature DB >> 739974

Cold-sensitivity of a double mutant strain combining two ribosomal mutations in the ascomycete Podospora anserina.

M Crouzet, J Bégueret.   

Abstract

A double mutant strain combining two ribosomal mutations conferring resistance to cycloheximide exhibits a cold-sensitive phenotype. At low temperature the biosynthesis of the 60S subunit is impaired. Genetic analysis of cold-resistant revertants have shown that this double mutant strain can be used efficiently to isolate new ribosomal mutations.

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Year:  1978        PMID： 739974     DOI： 10.1007/bf00332528

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  12 in total

1.  Ribosomal suppressors and antisuppressors in Podospora anserina: resistance to cycloheximide.

Authors:  E Coppin-Raynal
Journal:  J Bacteriol       Date:  1977-09       Impact factor: 3.490

2.  Cold-sensitive growth of a mutant of Escherichia coli with an altered ribosomal protein S8: analysis of revertants.

Authors:  D Geyl; A Böck; H G Wittmann
Journal:  Mol Gen Genet       Date:  1977-04-29

3.  Cold-sensitive mutants in Aspergillus nidulans. II. Mutations affecting ribosome production.

Authors:  C Waldron; C F Roberts
Journal:  Mol Gen Genet       Date:  1974

4.  Cold-sensitive mutations in Salmonella typhimurium which affect ribosome synthesis.

Authors:  P C Tai; D P Kessler; J Ingraham
Journal:  J Bacteriol       Date:  1969-03       Impact factor: 3.490

5.  Structure and function of E. coli ribosomes. 8. Cold-sensitive mutants defective in ribosome assembly.

Authors:  C Guthrie; H Nashimoto; M Nomura
Journal:  Proc Natl Acad Sci U S A       Date:  1969-06       Impact factor: 11.205

6.  Ribosomal proteins in the fungus Podospora anserina: evidence for an electrophoretically altered 60S protein in a cycloheximide resistant mutant.

Authors:  J Begueret; M Perrot; M Crouzet
Journal:  Mol Gen Genet       Date:  1977-11-14

7.  Cold-sensitive mutants of Drosophila melanogaster defective in ribosome assembly.

Authors:  E V Falke; T R Wright
Journal:  Genetics       Date:  1975-12       Impact factor: 4.562

8.  Mutation in Saccharomyces cerevisiae conferring streptomycin and cold sensitivity by affecting ribosome formation and function.

Authors:  F T Bayliss; J L Ingrahm
Journal:  J Bacteriol       Date:  1974-05       Impact factor: 3.490

9.  Genetic studies on cycloheximide-resistant strains of Schizosaccharomyces pombe.

Authors:  M A Ibrahim; A Coddington
Journal:  Heredity (Edinb)       Date:  1976-10       Impact factor: 3.821

10.  Neurospora crassa cytoplasmic ribosomes: cold-sensitive mutant defective in ribosomal ribonucleic acid synthesis.

Authors:  P J Russell; J R Hammett; E U Selker
Journal:  J Bacteriol       Date:  1976-03       Impact factor: 3.490
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  5 in total

1.  Pleiotropic changes in cycloheximide-resistant insect cell clones.

Authors:  N Nouri; A M Fallon
Journal:  In Vitro Cell Dev Biol       Date:  1987-03

2.  Analysis of revertants of a ribosomal mutation in Podospora anserina: evidence for new ribosomal mutations which confer hypersensitivity to paromomycin.

Authors:  N Randsholt; F Ibarrondo; M Dequard; M Picard-Bennoun
Journal:  Biochem Genet       Date:  1982-06       Impact factor: 1.890

3.  Mutations affecting translational fidelity in the eucaryote Podospora anserina: characterization of two ribosomal restrictive mutations.

Authors:  M Picard-Bennoun
Journal:  Mol Gen Genet       Date:  1981

4.  A new mutant form of the ribosomal protein L21 in the fungus Podospora anserina: identification of the structural gene for this protein.

Authors:  M Crouzet; J Begueret
Journal:  Mol Gen Genet       Date:  1980

5.  Construction and characterization of Chinese hamster cell EmtA EmtB double mutants.

Authors:  S Chang; J J Wasmuth
Journal:  Mol Cell Biol       Date:  1983-05       Impact factor: 4.272
  5 in total

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