Literature DB >> 7396882

Kinetic measurements of the biliary excretion of metabolized compounds.

G M Powell, J G Jones, C G Curtis.   

Abstract

1. Rats received constant infusions of bromosulphophthalein or [carboxy-14C]cholic acid at a range of concentrations. 2. Kinetic parameters describing the biliary excretion of the compounds were determined. 3. The biliary excretion of both compounds could be described by the same kinetic parameters already calculated for phenolphthalein disulphate, which is excreted in the bile unchanged.

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Year:  1980        PMID： 7396882      PMCID： PMC1161903          DOI： 10.1042/bj1880561

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  4 in total

1.  Bile and urine as complementary pathways for the excretion of foreign organic compounds.

Authors:  P C Hirom; P Millburn; R L Smith
Journal:  Xenobiotica       Date:  1976-01       Impact factor: 1.908

2.  A model system for investigating the biliary excretion of an anion in the rat.

Authors:  G M Powell; J G Jones; A H Olavesen; C G Curtis
Journal:  Biochem J       Date:  1975-05       Impact factor: 3.857

3.  Biliary excretion of foreign compounds. Biphenyl, stilboestrol and phenolphthalein in the rat: molecular weight, polarity and metabolism as factors in biliary excretion.

Authors:  P Millburn; R L Smith; R T Williams
Journal:  Biochem J       Date:  1967-12       Impact factor: 3.857

4.  Species variations in the threshold molecular-weight factor for the biliary excretion of organic anions.

Authors:  P C Hirom; P Millburn; R L Smith; R T Williams
Journal:  Biochem J       Date:  1972-10       Impact factor: 3.857
  4 in total
  1 in total

1.  Uptake and action of a disulphonic stilbene (SITS) in the perfused guinea-pig liver: a comparison with bromsulphthalein.

Authors:  S C Rutishauser
Journal:  J Physiol       Date:  1983-01       Impact factor: 5.182
  1 in total

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