Literature DB >> 7387888

The antiandrogenic effect of progesterone on the hamster flank organ.

A J Vermorken, C M Goos, H M Roelofs.   

Abstract

Progesterone, topically applied, prevents the stimulation of the hamster flank organ by testosterone, but not by dihydrotestosterone. 5 alpha-Dihydroprogesterone does not prevent stimulation by either of the two androgenic hormones. Neither progesterone nor 5 alpha-dihydroprogesterone stimulate the flank organ to any extent. Implications on the use of progesterone in acne therapy are discussed.

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Year:  1980        PMID: 7387888     DOI: 10.1111/j.1365-2133.1980.tb06560.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  3 in total

1.  Studies on the local activity of antiandrogens at the molecular and histological level.

Authors:  A J Vermorken; C M Goos; C Sultan; A M Vermeesch-Markslag; A C Dijkstra
Journal:  Mol Biol Rep       Date:  1986       Impact factor: 2.316

2.  An improved method for evaluating antiandrogens.

Authors:  C M Goos; P Wirtz; A J Vermorken
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

3.  The local antiandrogenic effect of the intracutaneous injection of progesterone in the flank organ of sexually mature male Syrian golden hamster.

Authors:  N Orentreich; J R Matias; V Malloy
Journal:  Arch Dermatol Res       Date:  1984       Impact factor: 3.017

  3 in total

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