Literature DB >> 7387402

Toxicological studies of liver cells by microspectrofluorometry.

A Stier, K H Nolte, A Schlenker, W Schumann, F M Zuretti.   

Abstract

The kinetics of xenobiotic biotransformation was measured in single, isolated, perifused liver cells with microspectrofluorometry using highly sensitive photodetection systems. A program of further applications to biochemical toxicological problems is presented.

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Year:  1980        PMID： 7387402     DOI： 10.1007/bf00303182

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  10 in total

1.  Measurement of protein rotational diffusion in membranes by flash photolysis.

Authors:  R J Cherry
Journal:  Methods Enzymol       Date:  1978       Impact factor: 1.600

2.  Lateral transport on cell membranes: mobility of concanavalin A receptors on myoblasts.

Authors:  J Schlessinger; D E Koppel; D Axelrod; K Jacobson; W W Webb; E L Elson
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205

3.  Functional heterogeneity of rat liver parenchyma and of isolated hepatocytes.

Authors:  D Sasse; N Katz; K Jungermann
Journal:  FEBS Lett       Date:  1975-09-01       Impact factor: 4.124

4.  The continuous kinetic determination of p-nitroanisole O-demethylation in hemoglobin-free perfused rat liver.

Authors:  R G Thurman; D P Marazzo; L S Jones; F C Kauffman
Journal:  J Pharmacol Exp Ther       Date:  1977-05       Impact factor: 4.030

5.  The rotational diffusion of cytochrome b5 in lipid bilayer membranes. Influence of the lipid physical state.

Authors:  W L Vaz; R H Austin; H Vogel
Journal:  Biophys J       Date:  1979-06       Impact factor: 4.033

6.  The O-dealkylation of 7-ethoxycoumarin by liver microsomes. A direct fluorometric test.

Authors:  V Ullrich; P Weber
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-07

7.  Microfluorimetric analysis of the cytochrome P448 associated, ethoxyresorufin O-deethylase activities of individual isolated rat hepatocytes.

Authors:  M D Burke; H Hallman
Journal:  Biochem Pharmacol       Date:  1978       Impact factor: 5.858

8.  The effect of albumin on the metabolism of ethoxyresorufin through O-deethylation and sulphate-conjugation using isolated rat hepatocytes.

Authors:  M D Burke; S Orrenius
Journal:  Biochem Pharmacol       Date:  1978       Impact factor: 5.858

Review 9.  Studies on metabolic events in localized compartments of the living cell by rapid microspectrofluorometry.

Authors:  E Kohen; B Thorell; C Kohen; J M Salmon
Journal:  Adv Biol Med Phys       Date:  1974-06

10.  Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.

Authors:  M D Burke; R T Mayer
Journal:  Drug Metab Dispos       Date:  1974 Nov-Dec       Impact factor: 3.922
  10 in total
  1 in total

1.  Heterogeneity of biotransformation of fluoranthene in perifused liver cells.

Authors:  A Stier; A Schlenker; J Sidhu; W Kühnle; S A Finch
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553
  1 in total

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