| Literature DB >> 7387181 |
Abstract
The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giesmsa procedure. The addition of inorganic trivalent arsenic (Na2HAsO4) 10(-6) M and 2 x 10(-6) M induces a significant and dose-dependent increase of SCE. This phenomenon is as sensitive as the evidence of arsenic-induced chromosomal aberrations in vitro.Entities:
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Year: 1980 PMID: 7387181 DOI: 10.1007/bf00416927
Source DB: PubMed Journal: Arch Dermatol Res ISSN: 0340-3696 Impact factor: 3.017