Literature DB >> 7379944

2-Halogeno-ethanols as an uncoupler of phosphorylation in rat liver mitochondria.

S Ebina, Y Nagai.   

Abstract

2-Chloroethanol, 2-bromoethanol and 2,2,2-trifluoroethanol at a concentration of 0.79 vol.% stimulated state 4 respiration and released oligomycin inhibition of state 3 respiration. 2-Fluoroethanol and 1-propanol at the same concentration did not affect the respiration.

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Year:  1980        PMID: 7379944     DOI: 10.1007/bf01965784

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS--III. UNCOUPLING OF OXIDATIVE PHOSPHORYLATION IN A CONNECTIVE TISSUE (CARTILAGE) AND LIVER MITOCHONDRIA BY SALICYLATE ANALOGUES: RELATIONSHIP OF STRUCTURE TO ACTIVITY.

Authors:  M W WHITEHOUSE
Journal:  Biochem Pharmacol       Date:  1964-03       Impact factor: 5.858

2.  THE INTERACTION OF UNCOUPLING PHENOLS WITH MITOCHONDRIA AND WITH MITOCHONDRIAL PROTEIN.

Authors:  E C WEINBACH; J GARBUS
Journal:  J Biol Chem       Date:  1965-04       Impact factor: 5.157

3.  Lipid solubility as a factor influencing the activity of uncoupling phenols.

Authors:  H C HEMKER
Journal:  Biochim Biophys Acta       Date:  1962-09-10

4.  Techniques for the application of polarography to mitochondrial respiration.

Authors:  B HAGIHARA
Journal:  Biochim Biophys Acta       Date:  1961-01-01

5.  Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism.

Authors:  P MITCHELL
Journal:  Nature       Date:  1961-07-08       Impact factor: 49.962

6.  Antibiotics as tools for metabolic studies. I. A survey of toxic antibiotics in respiratory, phosphorylative and glycolytic systems.

Authors:  H A LARDY; D JOHNSON; W C McMURRAY
Journal:  Arch Biochem Biophys       Date:  1958-12       Impact factor: 4.013

7.  Reversible inhibition of the coupling between phosphorylation and oxidation.

Authors:  W F LOOMIS; F LIPMANN
Journal:  J Biol Chem       Date:  1948-04       Impact factor: 5.157

8.  3,5-di-tert-butyl-4-hydroxybenzylidenemalononitrile; a new powerful uncoupler of respiratory-chain phosphorylation.

Authors:  S Muraoka; H Terada
Journal:  Biochim Biophys Acta       Date:  1972-08-17

9.  Weak-acid uncouplers of oxidative phosphorylation. Mechanism of action on thin lipid membranes.

Authors:  A Finkelstein
Journal:  Biochim Biophys Acta       Date:  1970-04-07

10.  Inhibition of alpha-chymotrypsin by 2-halogeno-ethanols; comparisons with 2-methyl-ethanols and urea.

Authors:  S Ebina; T Kobayashi; Y Nagai
Journal:  Experientia       Date:  1979-08-15
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