Literature DB >> 7379919

Dexamethasone protection against the acute lethality of ethanol in mice.

F H Ross, K F Soliman, C A Walker.   

Abstract

The administration of dexamethasone (DXM, 2.00 mg/kg) 1 h prior to the injection of lethal doses of ethanol was found to offer complete protection against ethanol toxicity at doses up to 5.25 g/kg and partial protection using higher doses. It is suggested that DXM central action might be involved in the protection against ehanol toxicity.

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Year:  1980        PMID: 7379919     DOI: 10.1007/bf01975138

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  7 in total

1.  Diurnal variations in plasma corticosterone and growth hormone as corrlelated with regional variations in norepinephrine, dopamine and serotonin content of rat brain.

Authors:  M L Simon; R George
Journal:  Neuroendocrinology       Date:  1975       Impact factor: 4.914

2.  Reversal by sotalol of the respiratory depression induced in mice by ethanol.

Authors:  K Hayashida; A A Smith
Journal:  J Pharm Pharmacol       Date:  1971-09       Impact factor: 3.765

3.  Inhibition by propranolol of ethanol-induced narcosis.

Authors:  A Smith; K Hayashida; Y Kim
Journal:  J Pharm Pharmacol       Date:  1970-08       Impact factor: 3.765

4.  Effect of ethanol on the metabolism of brain catecholamines.

Authors:  A Carlsson; T Magnusson; T H Svensson; B Waldeck
Journal:  Psychopharmacologia       Date:  1973

5.  Brain serotonin and pituitary-adrenal function.

Authors:  J Vernikos-Danellis; P Berger; J D Barchas
Journal:  Prog Brain Res       Date:  1973       Impact factor: 2.453

6.  Dexamethasone-blockade of incremental response of plasma progesterone to cervical dilation or vasopressin infusion in early human pregnancy.

Authors:  P Fylling
Journal:  Acta Endocrinol (Copenh)       Date:  1972-03

7.  Dexamethasone suppression of ovulation in PMS-treated immature rats.

Authors:  K F Soliman; C A Walker
Journal:  Experientia       Date:  1977-03-15
  7 in total

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