| Literature DB >> 192574 |
Abstract
A single injection of 2.0 mg/kg dexamethasone (DXM) administered at 51 h after pregnant mare serum gonadatropin (PMS) treatment inhibited both ovulation and luteinization. S.c. injection of human chorionic gonadotropin (HGG) caused ovulation and luteinization in DXM-PMS-treated rats, whereas treatment with ACTH failed to overcome the DXM inhibitory effect. These findings are interpreted to indicate that DXM inhibits ovulation through a mechanism which might involve the central nervous system.Entities:
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Year: 1977 PMID： 192574 DOI： 10.1007/bf02002851
Source DB: PubMed Journal: Experientia ISSN： 0014-4754