Literature DB >> 7379820

Biochemical concept and synthesis of a radioiodinated phenylfatty acid for in vivo metabolic studies of the myocardium.

H J Machulla, M Marsmann, K Dutschka.   

Abstract

A biochemical concept is proposed for a radioiodinated fatty acid avoiding high iodine background in imaging studies of the myocardium. For this approach omega-(p-123I phenyl)-pentadecanoic acid is chosen and a method for synthesis and quality control described.

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Year:  1980        PMID： 7379820     DOI： 10.1007/bf00252480

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  3 in total

1.  USE OF RADIOIODINATED FATTY ACID FOR PHOTOSCANS OF THE HEART.

Authors:  J R EVANS; R W GUNTON; R G BAKER; D S BEANLANDS; J C SPEARS
Journal:  Circ Res       Date:  1965-01       Impact factor: 17.367

2.  Myocardial extraction of labeled long-chain fatty acid analogs (38509).

Authors:  N D Poe; G D Rovinson; N S MacDonald
Journal:  Proc Soc Exp Biol Med       Date:  1975-01

3.  Comparative evaluation of fatty acids labeled with C-11, Cl-34m, Br-77, and I-123 for metabolic studies of the myocardium: concise communication.

Authors:  H J Machulla; G Stöcklin; C Kupfernagel; C Freundlieb; A Höck; K Vyska; L E Feinendegen
Journal:  J Nucl Med       Date:  1978-03       Impact factor: 10.057
  3 in total
  31 in total

Review 1.  Future aspects of BMIPP.

Authors:  N Tamaki; K Morita; E Tsukamoto; Y Kawai
Journal:  Int J Card Imaging       Date:  1999-02

2.  Role of BMIPP imaging for risk stratification in patients with coronary artery disease.

Authors:  Nagara Tamaki
Journal:  J Nucl Cardiol       Date:  2005 Mar-Apr       Impact factor: 5.952

Review 3.  Tracers for metabolic imaging of brain and heart. Radiochemistry and radiopharmacology.

Authors:  G Stöcklin
Journal:  Eur J Nucl Med       Date:  1992

Review 4.  Synthesis and validation of fatty acid analogs radiolabeled by nonisotopic substitution.

Authors:  William C Eckelman; John W Babich
Journal:  J Nucl Cardiol       Date:  2007 May-Jun       Impact factor: 5.952

Review 5.  BMIPP-design and development.

Authors:  F F Knapp; J Kropp
Journal:  Int J Card Imaging       Date:  1999-02

Review 6.  Molecular and cellular basis of viable dysfunctional myocardium.

Authors:  Marina Bayeva; Konrad Teodor Sawicki; Javed Butler; Mihai Gheorghiade; Hossein Ardehali
Journal:  Circ Heart Fail       Date:  2014-07       Impact factor: 8.790

7.  New high yield Cu(I) assisted 123I radioiodination of 15(p-I-phenyl)-9-methyl pentadecanoic acid, a potential myocardial tracer.

Authors:  J Mertens; J Eersels; W Vanryckeghem
Journal:  Eur J Nucl Med       Date:  1987

Review 8.  Metabolic imaging using SPECT.

Authors:  Junichi Taki; Ichiro Matsunari
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-06       Impact factor: 9.236

9.  The metabolism of 15-p-[123I]-iodophenylpentadecanoic acid in a surgically induced canine model of regional ischemia.

Authors:  M P Hudon; D M Lyster; W R Jamieson; A K Qayumi; C Sartori; H Dougan
Journal:  Eur J Nucl Med       Date:  1990

10.  Efficacy of 15-(123I)-p-iodophenyl pentadecanoic acid (IPPA) in assessing myocardial metabolism in a model of reversible global ischemia.

Authors:  M P Hudon; D M Lyster; E W Jamieson; K A Qayumi; M C Kiess; L J Rosado; A P Autor; C Sartori; H Dougan; J van den Broek
Journal:  Eur J Nucl Med       Date:  1988
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