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Literature DB >> 7379674

Kupffer cell phagocytosis in relation to BSP clearance in liver and inflammatory bowel diseases.

Abstract

Experience using microaggregated human serum albumin for a Kupffer cell phagocytic capacity "stress test" in patients with liver and inflammatory bowel diseases is described. Each result has been related to a 1-hr BSP clearance in order to account for variations in liver blood flow. Kupffer cell clearances are reduced in proportion to BSP clearance in obstructive jaundice and in secondary biliary cirrhosis but are increased in patients with chronic hepatocellular inflmmation. Conversely Kupffer cell phagocytosis is often depressed in patients with alcoholic hepatitis. In Crohn's disease or ulcerative colitis RES function is normal unless patients are receiving corticosteroid suppression.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1980 PMID： 7379674 DOI： 10.1007/bf01395504

Source DB: PubMed Journal: Dig Dis Sci ISSN： 0163-2116 Impact factor: 3.199

22 in total

1. The estimation of hepatic blood flow using indocyanine green.

Authors: K REEMSTSMA; G C HOTTINGER; A C DEGRAFF; O CREECH
Journal: Surg Gynecol Obstet Date: 1960-03

2. Phagocytosis of heat-denatured human serum albumin labelled with 131I and its use as a means of investigating liver blood flow.

Authors: B BENACERRAF; G BIOZZI; B N HALPERN; C STIFFEL; D MOUTON
Journal: Br J Exp Pathol Date: 1957-02

3. The disappearance rate of colloidal radio-gold from the circulation and its application to the estimation, of liver blood flow in normal and cirrhotic subjects.

Authors: H VETTER; R FALKNER; A NEUMAYR
Journal: J Clin Invest Date: 1954-12 Impact factor: 14.808

4. Clearance of viable Salmonella strains by the isolated, perfused rat liver: a study of serum and cellular factors involved and of the effect of treatments with carbon tetrachloride or Salmonella enteritidis lipopolysaccharide.

Authors: G Ruggiero; R Utili; A Andreana
Journal: J Reticuloendothel Soc Date: 1977-02

Review 5. Physiology and physiopathology of the reticuloendothelial system.

Authors: T M Saba
Journal: Arch Intern Med Date: 1970-12

6. The kinetics of phagocytosis. 1. A study on the clearance of denatured bovine albumin and its competitive inhibition by denatured human albumin.

Authors: S J Normann
Journal: J Reticuloendothel Soc Date: 1973-12

4. The use of human albumin millimicrospheres tagged with 99mTc in the evaluation of the removal capacity of the reticuloendothelial system.

Authors: M Bolognesi; C Merkel; A Gatta
Journal: Eur J Nucl Med Date: 1987

5. Reticuloendothelial system and hepatocytic function in fulminant hepatic failure.

Authors: J Canalese; C D Gove; A E Gimson; S P Wilkinson; E N Wardle; R Williams
Journal: Gut Date: 1982-04 Impact factor: 23.059

5 in total

Kupffer cell phagocytosis in relation to BSP clearance in liver and inflammatory bowel diseases.

1. The estimation of hepatic blood flow using indocyanine green.

2. Phagocytosis of heat-denatured human serum albumin labelled with 131I and its use as a means of investigating liver blood flow.

3. The disappearance rate of colloidal radio-gold from the circulation and its application to the estimation, of liver blood flow in normal and cirrhotic subjects.

4. Clearance of viable Salmonella strains by the isolated, perfused rat liver: a study of serum and cellular factors involved and of the effect of treatments with carbon tetrachloride or Salmonella enteritidis lipopolysaccharide.

Review 5. Physiology and physiopathology of the reticuloendothelial system.

6. The kinetics of phagocytosis. 1. A study on the clearance of denatured bovine albumin and its competitive inhibition by denatured human albumin.

7. The essential role of the liver in detoxification of endotoxin.

8. Endotoxin-induced liver necrosis and intravascular coagulation in rats enhanced by portacaval collateral circulation.

9. Endotoxaemia and renal failure in cirrhosis and obstructive jaundice.

10. Reticuloendothelial cell dysfunction in diabetes and hyperlipidemia.

Review 1. Macrophage activation, chronic inflammation and gastrointestinal disease.

2. Functional hyposplenism in alcoholic liver disease: a toxic effect of alcohol?

3. Monocyte function in cirrhosis.

4. The use of human albumin millimicrospheres tagged with 99mTc in the evaluation of the removal capacity of the reticuloendothelial system.

5. Reticuloendothelial system and hepatocytic function in fulminant hepatic failure.