| Literature DB >> 3665971 |
M Bolognesi1, C Merkel, A Gatta.
Abstract
Liver uptake kinetics of 99mTc labelled millimicrospheres of human serum albumin (MM) was studied in 16 subjects. Every subject received four doses of MM intravenously. The uptake constant decreased progressively with increasing dose. The maximum liver removal capacity, a parameter which is independent of liver blood flow, was calculated according to the method of Iio and Wagner (1963). From these data we conclude that MM are taken up by the reticuloendothelial system (RES) with saturable kinetics, and they are suitable for clinical use to evaluate RES function in man.Entities:
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Year: 1987 PMID: 3665971 DOI: 10.1007/bf00252603
Source DB: PubMed Journal: Eur J Nucl Med ISSN: 0340-6997