Literature DB >> 7378233

Complement-mediated reactions to diazepam with Cremophor as solvent (Stesolid MR).

M S Hüttel, A Schou Olesen, E Stoffersen.   

Abstract

Changes in complement reactions are described in two patients exhibiting adverse reactions to Stesolid MR (diazepam with Cremophor as solvent). The recorded frequency of adverse reactions to Althesin, propandid and Stesolid MR suggests that the common solvent Cremophor is responsible for the adverse reactions.

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Year:  1980        PMID： 7378233     DOI： 10.1093/bja/52.1.77

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  15 in total

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3.  A new parenteral emulsion for the administration of taxol.

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7.  Suspected anaphylactic reaction to Cremophor EL.

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Review 8.  Pharmacological effects of formulation vehicles : implications for cancer chemotherapy.

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9.  Histamine release and hypotensive reactions in dogs by solubilizing agents and fatty acids: analysis of various components in cremophor El and development of a compound with reduced toxicity.

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