Literature DB >> 7377912

Development of alcoholism in adoptees raised apart from alcoholic biologic relatives.

R J Cadoret, C A Cain, W M Grove.   

Abstract

Male adoptees raised apart from alcoholic biologic parents were followed up and compared with adoptees of nonalcoholic biologic parents. Significant associations were found between adoptee alcoholism and an alcoholic biologic background and between childhood conduct disorder and the development of alcoholism as an adult. None of the environmental factors--psychiatric or alcohol problems in adoptive family, socioeconomic status of the adoptive family, or exposure to discontinuous mothering as an infant--predicted adoptee alcoholism. These findings suggest the importance of a genetic factor in alcoholism and are in accord with previous work that failed to show an independent effect of an alcoholic environment in development of adoptee alcoholism.

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Year:  1980        PMID: 7377912     DOI: 10.1001/archpsyc.1980.01780180075008

Source DB:  PubMed          Journal:  Arch Gen Psychiatry        ISSN: 0003-990X


  26 in total

1.  Genetic disposition to alcoholism. An EEG study in alcoholics and their relatives.

Authors:  P Propping; J Krüger; N Mark
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

2.  Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.

Authors:  K J Buck; P Metten; J K Belknap; J C Crabbe
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

Review 3.  Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse.

Authors:  George R Breese; Rajita Sinha; Markus Heilig
Journal:  Pharmacol Ther       Date:  2010-10-15       Impact factor: 12.310

Review 4.  Adoption studies in functional psychosis.

Authors:  E Kringlen
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1991       Impact factor: 5.270

5.  The familial transmission of alcoholism.

Authors:  E J Marshall; R M Murray
Journal:  BMJ       Date:  1991-07-13

6.  Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats.

Authors:  C L Ehlers; R I Chaplin; T L Wall; L Lumeng; T K Li; M J Owens; C B Nemeroff
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

Review 7.  Information processing, neuropsychological function, and the inherited predisposition to alcoholism.

Authors:  J B Peterson; R O Pihl
Journal:  Neuropsychol Rev       Date:  1990-12       Impact factor: 7.444

Review 8.  Cognitive impairments in abstinent alcoholics.

Authors:  G Fein; L Bachman; S Fisher; L Davenport
Journal:  West J Med       Date:  1990-05

9.  Segregation analysis of alcoholism in families ascertained through a pair of male alcoholics.

Authors:  C E Aston; S Y Hill
Journal:  Am J Hum Genet       Date:  1990-05       Impact factor: 11.025

Review 10.  The genetic components of alcohol and nicotine co-addiction: from genes to behavior.

Authors:  Isabel R Schlaepfer; Nicole R Hoft; Marissa A Ehringer
Journal:  Curr Drug Abuse Rev       Date:  2008-06
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