Literature DB >> 2190421

Cognitive impairments in abstinent alcoholics.

G Fein1, L Bachman, S Fisher, L Davenport.   

Abstract

Impaired cognitive functioning in alcoholics is widespread during the first months of detoxification. Between half and two thirds of abstinent alcoholics exhibit cognitive impairments during this period, with residual deficits persisting for years after detoxification in some patients. The most severe deficits have been observed in visuospatial abilities, perceptual-motor integration, abstract reasoning, and new learning. The most significant predictors of cognitive dysfunction in persons recovering from alcoholism are the time elapsed since the last drink and the person's age. Surprisingly, the pattern and duration of a patient's alcohol abuse are relatively weak determinants of neuropsychological impairment during abstinence. Research investigating the hypothesis that cognitive impairments may be related to alcoholic persons resuming drinking has yielded mixed results, but a higher level of neuropsychological functioning is associated with increased rates of completing treatment programs and with greater success in the work environment after discharge from treatment. The possibility of cognitive limitations should be taken into account in planning treatment programs for alcoholism.

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Year:  1990        PMID: 2190421      PMCID: PMC1002406     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  81 in total

1.  Cognitive functioning of alcoholic females: an exploratory study.

Authors:  F R Sparadseo; W Zwick; N Butters
Journal:  Drug Alcohol Depend       Date:  1983-10       Impact factor: 4.492

2.  A comparison of the effects of long-term alcohol abuse and aging on the performance of verbal and nonverbal divided attention tasks.

Authors:  J T Becker; N Butters; A Hermann; N D'Angelo
Journal:  Alcohol Clin Exp Res       Date:  1983       Impact factor: 3.455

3.  Length of stay, neuropsychological performance, and aftercare: influences on alcohol treatment outcome.

Authors:  R D Walker; D M Donovan; D R Kivlahan; M R O'Leary
Journal:  J Consult Clin Psychol       Date:  1983-12

4.  Event-related brain potentials are different in individuals at high and low risk for developing alcoholism.

Authors:  R Elmasian; H Neville; D Woods; M Schuckit; F Bloom
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

5.  Cognitive loss and recovery in long-term alcohol abusers.

Authors:  J Brandt; N Butters; C Ryan; R Bayog
Journal:  Arch Gen Psychiatry       Date:  1983-04

6.  Differential improvement of cognitive functions in recovering alcoholic women.

Authors:  M S Fabian; O A Parsons
Journal:  J Abnorm Psychol       Date:  1983-02

7.  Recoverability of psychological functioning following alcohol abuse: prolonged visual-spatial dysfunction in older alcoholics.

Authors:  M S Goldman; D L Williams; D K Klisz
Journal:  J Consult Clin Psychol       Date:  1983-06

8.  Neuropsychological and computerized tomographic evaluations of young alcoholics.

Authors:  K Lee; E Jensen; P Bech
Journal:  Br J Psychiatry       Date:  1982-09       Impact factor: 9.319

9.  The young male alcoholic. A pilot study.

Authors:  E S Gomberg
Journal:  J Stud Alcohol       Date:  1982-07

10.  The alcoholic brain: CT scan and psychological findings.

Authors:  M A Ron
Journal:  Psychol Med Monogr Suppl       Date:  1983
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  64 in total

1.  Selective neurocognitive deficits and poor life functioning are associated with significant depressive symptoms in alcoholism-HIV infection comorbidity.

Authors:  Stephanie A Sassoon; Margaret J Rosenbloom; Rosemary Fama; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Psychiatry Res       Date:  2012-05-29       Impact factor: 3.222

Review 2.  Neurocircuitry in alcoholism: a substrate of disruption and repair.

Authors:  Edith V Sullivan; Adolf Pfefferbaum
Journal:  Psychopharmacology (Berl)       Date:  2005-09-14       Impact factor: 4.530

3.  Delta and theta oscillations as risk markers in adolescent offspring of alcoholics.

Authors:  Madhavi Rangaswamy; Kevin A Jones; Bernice Porjesz; David B Chorlian; Ajayan Padmanabhapillai; Chella Kamarajan; Samuel Kuperman; John Rohrbaugh; Sean J O'Connor; Lance O Bauer; Marc A Schuckit; Henri Begleiter
Journal:  Int J Psychophysiol       Date:  2006-11-28       Impact factor: 2.997

4.  Effects of chronic alcohol dependence and chronic cigarette smoking on cerebral perfusion: a preliminary magnetic resonance study.

Authors:  Stefan Gazdzinski; Timothyc Durazzo; Geon-Ho Jahng; Frank Ezekiel; Peter Banys; Dieterj Meyerhoff
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5.  Neural correlates of impulsive aggressive behavior in subjects with a history of alcohol dependence.

Authors:  Samet Kose; Joel L Steinberg; F Gerard Moeller; Joshua L Gowin; Edward Zuniga; Zahra N Kamdar; Joy M Schmitz; Scott D Lane
Journal:  Behav Neurosci       Date:  2015-02-09       Impact factor: 1.912

Review 6.  Neuroinflammation as a neurotoxic mechanism in alcoholism: commentary on "Increased MCP-1 and microglia in various regions of human alcoholic brain".

Authors:  Edith V Sullivan; Natalie M Zahr
Journal:  Exp Neurol       Date:  2008-07-14       Impact factor: 5.330

7.  Prefrontal cortical volume reduction associated with frontal cortex function deficit in 6-week abstinent crack-cocaine dependent men.

Authors:  George Fein; Victoria Di Sclafani; Dieter J Meyerhoff
Journal:  Drug Alcohol Depend       Date:  2002-09-01       Impact factor: 4.492

8.  Cognitive performance in long-term abstinent elderly alcoholics.

Authors:  George Fein; Shannon McGillivray
Journal:  Alcohol Clin Exp Res       Date:  2007-09-14       Impact factor: 3.455

9.  Neurocognition and inhibitory control in polysubstance use disorders: Comparison with alcohol use disorders and changes with abstinence.

Authors:  Thomas P Schmidt; David L Pennington; Stephanie L Cardoos; Timothy C Durazzo; Dieter J Meyerhoff
Journal:  J Clin Exp Neuropsychol       Date:  2016-10-03       Impact factor: 2.475

10.  Frontal Callosal Fiber Integrity Selectively Predicts Coordinated Psychomotor Performance in Chronic Alcoholism.

Authors:  Margaret J Rosenbloom; Stephanie A Sassoon; Rosemary Fama; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Brain Imaging Behav       Date:  2008       Impact factor: 3.978

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