Literature DB >> 7375942

Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.

D M Goldenberg, E E Kim, F H DeLand, J R van Nagell, N Javadpour.   

Abstract

Injection of iodine-131-labeled goat immunoglobulin G antibody to human chorionic gonadotropin (hCG) into patients with hCG-secreting trophoblastic and germinal tumors permitted tumor detection and location by external gamma-ray scintigraphy. Excision of one of the metastatic tumors located by this method indicated a tumor/nontumor ration of 39.29. The method appears to offer a new clinical tool for precisely locating hCG-producing tumors in the body, even when tumor identification by other clinical methods has failed.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7375942     DOI： 10.1126/science.7375942

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

Review 1.  Immunoscintigraphy for cancer detection: "a thousand ills require a thousand cures".

Authors:  S H de Bie; T C Ferreira; E K Pauwels; F J Cleton
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  A comparative distribution study of 111In-labeled DTPA and TTHA monoclonal antibody conjugates in a choriocarcinoma xenograft model.

Authors:  R G Buckley; P Barnett; F Searle; R Pedley; J A Boden
Journal:  Eur J Nucl Med       Date:  1986

3.  A potent and specific immunotoxin for tumor cells expressing disialoganglioside GD2.

Authors:  K Mujoo; R A Reisfeld; L Cheung; M G Rosenblum
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

4.  Modification of methyliminodiacetato-trans-R,R-1,2-diamminocyclohexane platinum(II) pharmacology using a platinum-specific monoclonal antibody.

Authors:  M G Rosenblum; J L Murray; S Stuckey; R A Newman; S Chaney; A R Khokhar
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

5.  Comparative clinical pharmacology of [111In]-labeled murine monoclonal antibodies.

Authors:  M G Rosenblum; J L Murray; L Lamki; G David; D Carlo
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

6.  Neutron-capture therapy of human cancer: in vitro results on the preparation of boron-labeled antibodies to carcinoembryonic antigen.

Authors:  E Mizusawa; H L Dahlman; S J Bennett; D M Goldenberg; M F Hawthorne
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

7.  Radioimmunolocalization of human brain tumours: biodistribution of radiolabelled monoclonal antibody UJ13A.

Authors:  R B Richardson; A G Davies; S P Bourne; G E Staddon; D H Jones; J T Kemshead; H B Coakham
Journal:  Eur J Nucl Med       Date:  1986

Review 8.  Antibody-mediated targeting in the treatment and diagnosis of cancer: an overview.

Authors:  C H Ford; A G Casson
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

9.  Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues.

Authors:  J P Brown; R G Woodbury; C E Hart; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

10.  Human breast tumor imaging using 111In labeled monoclonal antibody: athymic mouse model.

Authors:  B A Khaw; J S Bailes; S L Schneider; J Lancaster; J Powers; H W Strauss; J C Lasher; W L McGuire
Journal:  Eur J Nucl Med       Date:  1988
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.