Literature DB >> 7373718

Reovirus progeny subviral particles synthesize uncapped mRNA.

H Zarbl, D Skup, S Millward.   

Abstract

Reovirus progeny subviral particles were isolated from L-cells at late times postinfection. It has been shown (D. Skup and S. Millward, J. Virol. 34: 490--496, 1980) that these progeny subviral particles have masked capping enzymes, indicating that mRNA synthesized by these particles should be uncapped. When progeny subviral particles were used for mRNA synthesis in vitro, they failed to incorporate the beta-phosphate of [beta-32P]GTP into the 5' terminal. Direct analysis of reovirus mRNA synthesized by progeny subviral particles in the presence of either [alpha-32P]GTP or [alpha-32P]CTP indicated that the 5' terminal was uncapped, having the structure pGpC... The implications of this finding to the reovirus replicative cycle are discussed.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7373718      PMCID： PMC288729     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  35 in total

1.  Polypeptide components of virions, top component and cores of reovirus type 3.

Authors:  R E Smith; H J Zweerink; W K Joklik
Journal:  Virology       Date:  1969-12       Impact factor: 3.616

2.  RNA polymerase activity in purified reoviruses.

Authors:  A J Shatkin; J D Sipe
Journal:  Proc Natl Acad Sci U S A       Date:  1968-12       Impact factor: 11.205

3.  Fate of parental reovirus in infected cell.

Authors:  C T Chang; H J Zweerink
Journal:  Virology       Date:  1971-12       Impact factor: 3.616

4.  Temperature-sensitive mutants of reovirus type 3 features of genetic recombination.

Authors:  B N Fields
Journal:  Virology       Date:  1971-10       Impact factor: 3.616

5.  Studies on the in vitro transcription of reovirus RNA catalyzed by reovirus cores.

Authors:  J J Skehel; W K Joklik
Journal:  Virology       Date:  1969-12       Impact factor: 3.616

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Ribonucleoside triphosphate-dependent pyrophosphate exchange of Reovirus cores.

Authors:  J T Wachsman; D H Levin; G Acs
Journal:  J Virol       Date:  1970-10       Impact factor: 5.103

8.  An improved method for thin-layer chromatography of nucleotide mixtures containing 32P-labelled orthophosphate.

Authors:  M Cashel; R A Lazzarini; B Kalbacher
Journal:  J Chromatogr       Date:  1969-03-11

9.  Separation of ten reovirus genome segments by polyacrylamide gel electrophoresis.

Authors:  A J Shatkin; J D Sipe; P Loh
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103

10.  Asynchronous synthesis of the complementary strands of the reovirus genome.

Authors:  M Schonberg; S C Silverstein; D H Levin; G Acs
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205
View more
  16 in total

1.  Reovirus sigmaNS protein is required for nucleation of viral assembly complexes and formation of viral inclusions.

Authors:  M M Becker; M I Goral; P R Hazelton; G S Baer; S E Rodgers; E G Brown; K M Coombs; T S Dermody
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

2.  Viral RNA at Two Stages of Reovirus Infection Is Required for the Induction of Necroptosis.

Authors:  Angela K Berger; Bradley E Hiller; Deepti Thete; Anthony J Snyder; Encarnacion Perez; Jason W Upton; Pranav Danthi
Journal:  J Virol       Date:  2017-02-28       Impact factor: 5.103

3.  Cell Entry-Independent Role for the Reovirus μ1 Protein in Regulating Necroptosis and the Accumulation of Viral Gene Products.

Authors:  Katherine E Roebke; Pranav Danthi
Journal:  J Virol       Date:  2019-05-15       Impact factor: 5.103

4.  The viral protein sigma 3 participates in translation of late viral mRNA in reovirus-infected L cells.

Authors:  R Lemieux; G Lemay; S Millward
Journal:  J Virol       Date:  1987-08       Impact factor: 5.103

5.  mRNA capping enzymes are masked in reovirus progeny subviral particles.

Authors:  D Skup; S Millward
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

6.  Nonstructural Protein σ1s Is Required for Optimal Reovirus Protein Expression.

Authors:  Matthew B Phillips; Johnasha D Stuart; Emily J Simon; Karl W Boehme
Journal:  J Virol       Date:  2018-03-14       Impact factor: 5.103

7.  Mammalian orthoreovirus escape from host translational shutoff correlates with stress granule disruption and is independent of eIF2alpha phosphorylation and PKR.

Authors:  Qingsong Qin; Kate Carroll; Craig Hastings; Cathy L Miller
Journal:  J Virol       Date:  2011-06-29       Impact factor: 5.103

8.  mRNA discrimination in extracts from uninfected and reovirus-infected L-cells.

Authors:  R Lemieux; H Zarbl; S Millward
Journal:  J Virol       Date:  1984-07       Impact factor: 5.103

9.  Regulation of expression of the wound tumor virus genome in persistently infected vector cells is related to change in translational activity of viral transcripts.

Authors:  A J Peterson; D L Nuss
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

10.  Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication.

Authors:  Paula F Zamora; Liya Hu; Jonathan J Knowlton; Roni M Lahr; Rodolfo A Moreno; Andrea J Berman; B V Venkataram Prasad; Terence S Dermody
Journal:  J Virol       Date:  2018-07-17       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.