| Literature DB >> 7367997 |
D M Becker, E Cayanis, S Kramer.
Abstract
The porphyrin precursor delta-aminolevulinic acid (delta-ALA) is a structural analogue of the putative amino acid neurotransmitter, gamma-aminobutyric acid (GABA). This study has demonstrated that delta-ALA has no effect on glutamate decarboxylase activity and only a small inhibitory effect of GABA aminotransferase activity. This would suggest that if accumulation of delta-ALA is related to development of the acute attack of porphyria, it is not via an effect on GABA synthesis and metabolism.Entities:
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Year: 1980 PMID： 7367997
Source DB: PubMed Journal: S Afr Med J